Amiodarone Flashcards
1
Q
Amiodarone: Full name
A
Amiodarone Hydrochloride
2
Q
Amiodarone: Trade names
A
- Coradarone
- Pacerone
- Nexterone
3
Q
Amiodarone: Class
A
Antiarrhythmic
4
Q
Amiodarone: Action
A
- blocks sodium, potassium, and calcium channels in cardiac cells
Slows conduction and prolongs repolarization - Has alpha and beta adrenergic blocking properties, causing negative inotropic effects and reduces peripheral vascular resistance (AFTERLOAD)
5
Q
Amiodarone: Onset/Duration
A
Onset: minutes
Duration: days
6
Q
Amiodarone: Indications
A
- Stable VT
- Reported/witnessed ≥ AICD firing
OR ≥ 1 AED shock delivered with pulses ≥ 60 - VF/pulseless VT: After 1st shock if still refractory
7
Q
Amiodarone: Dosage/Route for stable VT
A
ADULT only (SO): - 150mg in 100ml of NS over 10” IV/IO (piggyback)
MR x1 in 10” (SO)
8
Q
Amiodarone:
Dosage/Route
- for ≥ AICD firing or ≥ 1 AED shock (with pulse ≥ 60)
A
Adult Only, (SO):
- 150mg in 100ml of NS over 10” IV/IO piggyback… SO
9
Q
Amiodarone:
Dosage/Route
- for VF/pulseless VT
A
Adult:
300mg IV/IO SO; MR 150mg (max 450mg) .. SO
PEDS:
PDC IV/IO (SO) MR x1 in 3-5” SO
10
Q
Amiodarone: Contraindications
A
- hypotension
- 2nd and 3rd degree heart block
- Idioventricular rhythms
11
Q
Amiodarone: Side effects
A
- Hypotension
- Exacerbation of presenting arrhythmia
- Liver injury
- Pulmonary injury, pulmonary infiltrates, bronchospasm, SOB cough hemoptysis, hypoxia
12
Q
Amiodarone: Packaging
A
150mg / 3 ml
13
Q
Amiodarone: Administration
A
Piggyback infusion in 100ml of NS over 10 minutes
- drip rate with 60ggts/ml tubing = 10 gtts/second
