Acetaminophen (tylenol)

Question 1

Acetaminophen: Class

Answer 1

Analgesic/Antipyretic

Question 2

Acetaminophen: Action

Answer 2

• Inhibits the synthesis of prostaglandins, which transmit pain signals and induce fever.
• Reduces pain by blocking the signals produced by prostaglandins

Question 3

Acetaminophen: Onset and Duration

Answer 3

Onset = 15 minute
Peak = 1 hour

Duration = up to 4-6 hours

Question 4

Acetaminophen: Indications

Answer 4

For Treatment of Pain As Needed:

• Abdominal Pain
• Burns
• Envenomation Injury
• Trauma

Question 5

Acetaminophen: Dosage/Route

Answer 5

Adult:
1000mg IV x1 SO
Infuse over 15 minutes

PEDS:
≥ 2 y/o, PDC x1 SO
Infuse over 15 minutes

Maximum daily dose =4,000mg in 24 hours

Question 6

Acetaminophen… BHPO required for:

Answer 6

Isolated head injury 
Acute onset of severe Headache
Drug/ETOH intoxication 
Multiple trauma with GCS < 15
Suspected active labor

Question 7

Acetaminophen: Maximum daily dose

Answer 7

4,000mg in 24 hours

Question 8

Acetaminophen: Contraindications

Answer 8

< 2 years old
Severe hepatic (liver) impairment
Severe active liver disease
If known or suspected total dose exceeding 4000mg in a 24 hr period

Question 9

Acetaminophen: Side effects

Answer 9

Nausea, vomiting
Headache, sleep problems
Constipation
Itching, agitation
Partial or total lung collapse in pediatric patients

Question 10

Acetaminophen: Packaging

Answer 10

1000mg / 100ml (10mg/1ml)