Amides Flashcards
1
Q
Preparation of Amides
A
- Acyl chloride with conc. ammonia
2
Q
Acyl chloride with conc. ammonia
A
Type of reaction: addition-elimination
Condition: mix at room temperature
Change in functional group: acyl chloride –> amide
3
Q
With H+ or OH-
A
Type of reaction: hydrolysis
amide + H+ –> carboxylic acid + NH4+
amide + OH- –> carboxylate anion + NH3
carboxylate anion + H+ (excess strong acid) –> carboxylic acid