Alveoli Flashcards

1
Q

What is the primary site of gas exchange?

A

Alveoli

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2
Q

What are alveoli?

A

They are small outpockets which greatly increase the surface area for gas exchange

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3
Q

What is a lung lobule?

A

A cluster of alveoli supplied by a single respiratory bronchiole surrounded by the connective tissue of the lung

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4
Q

What are some characteristics of the alveoli?

A

They have extremely thin walls (only one cell thick) with basement membranes fused to the endothelium of the capillaries that surround them

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5
Q

What is the apical surface the alveoli’s covered in?

A

Surfactant

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6
Q

What is emphysema?

A

A condition associated with smoking. It is caused by gradual damage to the alveoli by irritants or infection which causes them to lose their natural elasticity

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7
Q

What happens if alveoli lose their natural elasticity?

A

Lungs are unable to expel all the air on expiration and leaves them over inflated and the patient struggles to force air in and out of their lungs

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8
Q

What does reduced ventilation in the lungs cause?

A

Chronic hypoxia causing fatigue and weight loss

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9
Q

What is emphysema often associated with?

A

Chronic bronchitis where the lungs are able to clear mucus

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10
Q

What is the combination of emphysema and chronic bronchitis called?

A

Chronic obstructive pulmonary disease (COPD)

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11
Q

Is there a cure for emphysema?

A

No but it can be controlled with bronchodilators

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12
Q

What is a common chronic airway disease?

A

Asthma

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13
Q

What does asthma do?

A

Difficulty breathing as the conducting airways become restricted as the diameter reduces

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14
Q

What type of disease is asthma?

A

An immunological disease, caused by the immune system over reacting to an antigen that would normally be overlooked

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15
Q

What is an inducer in asthma?

A

The original antigen that elicited an immune response

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16
Q

What happens on exposure to the antigen when the body gives an inappropriate response?

A

Causes swelling of the airways and recruitment of eosinophils

17
Q

What is status asthmaticus?

A

An acute asthma attack which is then later triggered by an irritant

18
Q

What is the treatment for asthma?

A

Bronchodilators such as salbutamol, steroids such as beclomethasone dipropionate (BDP) helps reduce the long-term airway damage