Alterations Of Neurological Function Flashcards

1
Q

What describes a feature of a concussion?

A

Causes a temporary disruption of neuronal activity

Mild to moderate brain injury causes by acceleration/deceleration forces.

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2
Q

The nurse is performing a triage assessment of a 17-year-old football player who sustained head trauma during a game. The nurse assesses for which signs of a concussion?

A

Loss of consciousness for 2 minutes following the injury
Momentary amnesia
Headache

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3
Q

What statement best describes post-concussion syndrome?

A

Physical, psychological and social problems up to one year following the concussion.

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4
Q

A 36-year-old woman sustains a traumatic brain injury during a motor vehicle collision. After 24 hours she is still unconscious and is diagnosed with ‘diffuse brain injury’. Diffuse brain injury is primarily caused by:

A

shearing and tearing of neurons.

The prolonged loss of consciousness in diffuse bran injury is generally caused by shearing and tearing of neurons, which often results in permanent brain damage.

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5
Q

Increased intracranial pressure (ICP) in diffuse brain injury is primarily caused by:

A

inflammation leading to cerebral edema.

In diffuse brain injury, damage to the neurons causes an inflammatory response. An inflammatory response results in increased capillary permeability, which causes fluid to rapidly diffuse out of the capillaries into the brain tissues, causing a condition defined as cerebral edema.

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6
Q

A personal with a spinal cord injury at T7 has paraplegia.

A

True

Paraplegia is defined as the loss of motor function to the lower extremities. This is caused by spinal cord injuries at or below T2. The upper extremities are innervated by nerves originating from C5-T1, therefore a spinal cord injury at T1 or above would start affecting the upper extremities. Spinal cord injuries at or above C5 cause complete quadriplegia.

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7
Q

A person with quadraplegia caused by a spinal cord injury at C5 will have a loss of sensation below the neck, but will have normal bowel and bladder function.

A

False

Paraplegia is defined as the loss of motor function to the upper and lower extremities and is caused by spinal cord injuries at or above C5. With complete spinal cord injuries, all function (motor, sensory, and autonomic) at or below the level of the injury is affected. Bowel and bladder function is controlled by autonomic nerves originating from S2-S4. An individual with quadriplegia (or paraplegia) has no sensation form the bowel and bladder, and no voluntary control over these organs.

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8
Q

Why is it difficult to determine if a person has permanent loss of function due to a spinal cord injury until 1-3 weeks following the injury?

A

Inflammation and the resulting edema can temporarily impair neuronal activity.

Immediately following a spinal cord injury there can be significant inflammation and edema in the spinal cord that can temporarily impair neuron function. Therefore it is difficult to tell what loss of function is permanent until the edema resolves. This stage is called spinal shock.

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9
Q

Which problem is a common trigger for autonomic dysreflexia in persons with spinal cord injuries?

A

Distended bladder

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10
Q

A client with quadraplegia is at risk for autonomic dysreflexia. What key vital sign chnage would indicate that he is developing this life-threatening condition?

A

Blood pressure = 220/95 mm Hg

Autonomic dysreflexia is a condition where activation of the sympathetic nervous system causes arterial vasoconstriction leading to severe hypertension.

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11
Q

All strokes cause:

A

cerebral ischemia.

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12
Q

What is a stroke?

A

cerebral ischemia resulting in the death of CNS neurons. The majority of strokes are caused by blood clots or a hemorrhage in a cerebral artery.

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13
Q

Often caused by small blood clots that form in the heart and travel up to the brain that cause temporary ischemia.

A

Transient ischemic attack (TIA)

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14
Q

Caused by a blood clot that develops in an atherosclerotic cerebral artery

A

Thrombotic stroke

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15
Q

Can be caused by a large blood clot in the carotid artery that travels to the brain.

A

Embolic stroke

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16
Q

Can be caused by an aneurysm

A

Hemorrhagic stroke

Ruptured cerebral artery leads to cerebral ischemia and increased intracranial pressure

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17
Q

In general, Alzheimer disease causes:

A

progressive dementia.

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18
Q

What is the definition of Alzheimer disease?

A

Causes a progressive failure of cerebral function not associated with an impaired level of consciousness, which is the definition of dementia.

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19
Q

The most significant risk factors in the development of late onset Alzheimer disease include:

A

Older age and genetics/family history.

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20
Q

In addition to memory loss and a decrease in the ability to recognize their loved ones, individuals with Alzheimer disease can also develop which problems?

A

Problems walking and increased risk of falling
Bowel and urinary incontinence
Mood disturbances and violent outbursts

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21
Q

Parkinson disease is caused by the the loss of _______________ secretion in the basal ganglia region of the brain and results in a wide variety of motor problems.

A

Dopamine

22
Q

The nurse is assessing a 72-year-old man in a primary care clinic. Which of the following cluster of signs might prompt the nurse to investigate whether he is developing Parkinson disease?

A

Muscle rigidity
Postural problems
Limb tremors
Bradykinesia

23
Q

What are risk factors for multiple sclerosis (MS)

A

Epstein Bar Virus (EBV) infection
Family history of multiple sclerosis (genetic risk factors)
Vitamin D deficiency

24
Q

Susan Taylor, 23, begins having problems with tiredness, weakness, and visual changes. Her diagnosis is multiple sclerosis (MS). The pathophysiology of multiple sclerosis includes:

A

demyelination of neurons in the central nervous system (CNS).

25
Q

Susan Taylor, age 29, begins having problems with tiredness, weakness, and visual changes. Her diagnosis is multiple sclerosis (MS). As her MS progresses, she begins to exhibit the following symptoms.

A

Trouble balancing and walking
Headaches
Urinary incontinence

26
Q

What isTraumatic Brain Injury?

A

Alteration in brain function caused by an external force.

27
Q

What are the clinical manifestations of concussion?

A

Results in momentary amnesia, visual disturbances, nausea/vomiting, headache, loss of consciousness (more severe concussions), etc

Concussion may have a cumulative effect.

28
Q

What are some concussion complications?

A

Post-concussion syndrome
Post-traumatic seizures
Chronic traumatic encephalopathy (CTE)

29
Q

What is post-concussion syndrome?

A

physical, psychological and social problems up to one year following the concussion

30
Q

What is post-traumatic seizures?

A

can occur within days following the injury and last up to 2-5 yrs

31
Q

What is Chronic traumatic encephalopathy (CTE)?

A

progressive dementia following repeated brain injury (generally associated with sports-related injuries from football and boxing)

32
Q

What is diffuse brain injury?

A

Severe brain injury causes by acceleration/deceleration or shear forces.

Defined by coma > 6 hours

33
Q

What is the main cause of diffuse brain injury?

A

Injury causes injury (tearing, shearing) to the neurons and blood vessels in the brain.

34
Q

What does neuronal injury in a traumatic brain injury stimulates?

A

Stimulates an inflammatory response resulting in cerebral edema, which leads to increased intracranial pressure (ICP).

Can result in permanent CNS dysfunction and brain death

35
Q

What is the best definition of a concussion?

A

Mild to moderate brain injury caused by acceleration/deceleration forces

36
Q

What causes increased intracranial pressure ICP?

A

Cerebral edema
Intracerebral hemorrhage
Hydrocephalus

37
Q

What are the early signs of increased ICP?

A

Headache
Blurred vision
Nausea and vomiting
Confusion, disorientation

38
Q

What are late signs of increased ICP?

A

Ipsilateral (same side) pupil dilation or fixed and dilated pupils.

Deterioration of level of consciousness/loss of consciousness.

Alterations in vital signs (BP, respirations)

39
Q

What is a spinal cord injury?

A

Complete or incomplete injury to the ascending and/or descending tracts of the spinal cord. Usually caused by vertebral injury. Other causes include tumor compression of spinal cord or ischemic stroke.

40
Q

What are the manifestations of Spinal Cord Injury?

A

Loss of sensation below the level of injury
Paralysis below the level of injury: Paraplegia, Quadriplegia.
Loss of parasympathetic function to the distal bowel and bladder.
Spinal Shock
Autonomic Dysreflexia

41
Q

What is paraplegia?

A

Paralysis to lower limbs

42
Q

What is quadriplegia?

A

Paralysis to the upper and lower limbs.

43
Q

What causes spinal shock?

A

Caused by disruption of action potentials and synaptic function, as well as spinal cord edema

44
Q

What is autonomic dysreflexia?

A

Sudden, massive sympathetic response to sensory stimulus below the SCI, causing severe hypertension and vasoconstriction.
Occurs after spinal shock has resolved.

45
Q

What are common acute manifestation of larger strokes?

A

Headache
Focal deficits
Confusion
Decreased level of consciousness (50%)

46
Q

What are common focal and general neurological deficits of larger strokes?

A

➢Hemiplegia – weakness or paralysis
➢Hemiparesis – numbness and tingling, loss of sensation
➢Loss of speech function (aphasia)
➢Swallowing difficulties (dysphagia)
➢‘Locked in syndrome’

47
Q

A large blood clot develops in a branch of a cerebral artery causing a severe reduction in blood flow to a specific region of the brain is called a/an:

A

thrombotic stroke

48
Q

What are the risk factors on developing early onset Alzheimer’s disease?

A

People age 30-60
Single-gene mutations.

49
Q

Early manifestations of Alzheimer disease include all of the following problems

A

becoming easily upset about minor problems.
short term memory loss.
urinary incontinence.

50
Q

What is a consequence of demyelination?

A

Inflammation
Causes scarring and formation of ‘plaques’ (characteristic brain lesions in MS)

51
Q

Multiple sclerosis is caused by:

A

autoimmune destruction of the myelin sheath of CNS neurons.