Alpha blockers

Question 1

alpha blockers indication

Answer 1

BPH first line and resistant hypertension

Question 2

alpha blockers MOA

Answer 2

selective for alpha adrenoceptor found in smooth muscle, blocking receptors induces relaxation so cause vasodilation and a fall in blood pressure and reduced resistance to bladder outflow

Question 3

alpha blockers side effects

Answer 3

postural hypotension, dizziness and syncope especially after first dose,

Question 4

Alpha blockers cautions

Answer 4

don’t use if existing postural hypotension

Question 5

Alpha blockers interactions

Answer 5

codyanamic effect may be sensible to stop other antihypertensives when taking first dose

Question 6

Alpha blocker examples

Answer 6

doxazosin, tamsulosin, alfusozin

Question 7

How to take alpha blockers

Answer 7

initially take at night to help with postural hypotension