Allergy and Anaphylaxis Clinical reasoning Flashcards
1
Q
What is a mast cell?
What is IgE?
A
- Ige cross linking- to release histamine - So allergen binds to - Fc receptor on Mast cell- causing massive release of histamine
IgE:
1) Normally produced the smallest amount (IgE) - Hypersensitivity
2) Need to be sensitized to
2
Q
What is anaphylaxis?
What clincial signs make it likely? What is the 1 of 2 criteria needed to fulfil?
A
- Acute onset illness with typical skin features (urticarial rash or erythema/flushing and or angiodema)
3
Q
What certain conditions are similair to anaphylaxis? (look similair clinically)
What is the definition of anaphylaxis?
A
4
Q
What factors and cofactors effect anaphylaxis?
- Excercise
- acute infection
3.
A
5
Q
Case 1: Just had peanut butter for the first time:
DDX urticaria?
A
6
Q
History and examination + DDX + investigation+ Management of
Urticaria
A
7
Q
What is chronic spontaneous urticaria?
A
