Allergy Flashcards
what is the simplified pathology of type I hypersensitivity
IgE mediated
what is the simplified pathology of type II hypersensitivity
direct cell killing
what mediates type II hypersensitivity reactions
IgM or IgG auto-antibodies
what is the simplified pathology of type III hypersensitivity
immune complex mediated
what is the simplified pathology of type IV hypersensitivity
cell mediated
what is the main cell involved in type IV hypersensitivity
Th1 lymphocytes
what type of hypersensitivity is a food allergy
type I
what type of hypersensitivity is Grave’s disease
type II
what type of hypersensitivity is sarcoidosis
type IV
what type of hypersensitivity is a blood transfusion reaction
type II
what type of hypersensitivity is rhinitis
type I
what type of hypersensitivity is pemphigus
type II
what type of hypersensitivity is contact dermatitis
type IV
what type of hypersensitivity is SLE
type III
what type of hypersensitivity is asthma
type I
what type of hypersensitivity is rheumatoid arthritis
type III
what type of hypersensitivity is pemphigus
type II
what type of hypersensitivity is TB
type IV
what test is used to diagnose type I hypersensitivity
skin prick test
what test is used to diagnose type IV hypersensitivty
patch test
which interleukins are involved in type I hypersensitivity
IL4, IL5, IL13
what is important in a history for differentiating type I and IV hypersensitivity
type I has immediate onset and type IV has delayed onset
what test can be performed during suspected anaphylaxis to confirm type I hypersensitivity
serum tryptase
what is the management of type I hypersensitivity if the patient is struggling to breath
adrenaline 300mg adult, 150mg child
