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Y2 DERM > Allergy > Flashcards

Allergy Flashcards

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Dermatology Board Prep flashcards
1
Q

what is the simplified pathology of type I hypersensitivity

A

IgE mediated

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2
Q

what is the simplified pathology of type II hypersensitivity

A

direct cell killing

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3
Q

what mediates type II hypersensitivity reactions

A

IgM or IgG auto-antibodies

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4
Q

what is the simplified pathology of type III hypersensitivity

A

immune complex mediated

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5
Q

what is the simplified pathology of type IV hypersensitivity

A

cell mediated

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6
Q

what is the main cell involved in type IV hypersensitivity

A

Th1 lymphocytes

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7
Q

what type of hypersensitivity is a food allergy

A

type I

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8
Q

what type of hypersensitivity is Grave’s disease

A

type II

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9
Q

what type of hypersensitivity is sarcoidosis

A

type IV

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10
Q

what type of hypersensitivity is a blood transfusion reaction

A

type II

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11
Q

what type of hypersensitivity is rhinitis

A

type I

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12
Q

what type of hypersensitivity is pemphigus

A

type II

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13
Q

what type of hypersensitivity is contact dermatitis

A

type IV

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14
Q

what type of hypersensitivity is SLE

A

type III

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15
Q

what type of hypersensitivity is asthma

A

type I

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16
Q

what type of hypersensitivity is rheumatoid arthritis

A

type III

17
Q

what type of hypersensitivity is pemphigus

A

type II

18
Q

what type of hypersensitivity is TB

A

type IV

19
Q

what test is used to diagnose type I hypersensitivity

A

skin prick test

20
Q

what test is used to diagnose type IV hypersensitivty

A

patch test

21
Q

which interleukins are involved in type I hypersensitivity

A

IL4, IL5, IL13

22
Q

what is important in a history for differentiating type I and IV hypersensitivity

A

type I has immediate onset and type IV has delayed onset

23
Q

what test can be performed during suspected anaphylaxis to confirm type I hypersensitivity

A

serum tryptase

24
Q

what is the management of type I hypersensitivity if the patient is struggling to breath

A

adrenaline 300mg adult, 150mg child

25
Q

what is the management of hypersensitivity if the patient isn’t struggling to breath

A

antihistamine e.g. chloramphenamine. PO prednisolone if it doesn’t settle 30minutes later

26
Q

what should be give instead of milk to a baby with a cows milk allergy

A

extensively hydrolysed infant formula

Y2 DERM (11 decks)

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