Allergy Flashcards
Disadvantage of serum specific IgE
High rate of false positives if elevated total IgE (non-specific binding)
What type of test is the serum specific IgE
ELISA
How many kids will outgrow a milk or egg allergy
80-90%
Percent of kids that will outgrow peanut allergy
20%
what infants are at high risk of developing food allergy?
those with a first degree relative with an allergic condition
what conditions (4) can be managed with immunotherapy
venom allergy, allergic rhinitis, allergic asthma, atopic dermatitis
penicillin anaphylaxis is mediated by….
IgE against a major determinant (only 10% a reaction to minor determinant)
percent of body surface area involved in toxic epidermal necrolysis
> 30%
percent of body surface area involved in steven johnsons syndrome
<10%
do you give the inactivated influenza vaccine in a kid with egg allergy?
YES, as single dose
definition of urticaria
elevated pruritic lesion lasting < 24 hrs
if a hive stays in same position > 48 hrs, what should you think of?
urticarial vasculitis, autoimmune condition
definition of chronic urticaria
lasts > 6 weeks
how do you manage urticaria
standard dose of 2nd generation non-sedating antihistamine
what do you do if urticaria doesn’t respond to standard dose of second generation non-sedating antihistamine, and symptoms persist x 2 weeks?
increase dose of antihistamine x 4
