Allergies/ Anaphylaxis Flashcards
Diapadesis
“oozing through”
Phagocytes
“phago” = eating
Macrophages
big eaters, white blood cells
Natural killer cells
binds to foreign cell and secrets enzyme
Antigen
Antibody generator
Antibody’s
Tag bad cells for phagocytes
- Purpose is to counteract effects of an antigen by binding and removing
- Body must have been previously exposed
B cells
Bone marrow produced
T cells
Thymus produced
Helper T’s
Call the shots
Memory T cells
Future immunity
Worst means of aquiring an allergic reaction is…
Injection (bee sting, penecilin injection)
Deaths from anaphylaxis per year
400-800 people die per year
Allergen
Substance that induces hypersensitivity
Allergy
exaggerated immune response
Autoimmunity
immune response against own cells
Isoimmunity
Immune response directed against beneficial foreign tissues (ex: Lupus Disease)
Immunoglobulin
Molecule produced to challenge a immunogen
Immunoglobulin seen in allergic reaction
IgE
Process of allergic reaction
slide 14
Mast cells
release histamines when the allergen is encountered
Types of reactions
Local
Systemic
Anaphylaxis (systemic, cutaneous- tissue, skin… everything swells)
First drug to be administered for anaphylaxis
Oxygen
order for epi IV/IO allergic reaction
.1mg IV/IO 1:10,000 BHO
What drugs cause extapyramidal reactions
Phenothiazines
Phenothiazines
Haldol - Psych Mellaril - Maintenance Navane Stelazine Compazine – Psych, N/V Thorazine Tigan – Inapsine Reglan - GI Torecan Emetecon Prolixin
Immunogen
Substance capable of immune response or producing immunity
Allergy
Antibody-antigen response
Altered body reaction to an antigen
Body’s defense system
- Skin is acidic, inhospitable to most bacteria
- If foreign substance enters body, the body tries to rid it through…cough, sloughing, vomiting, urinated
- Next step in inflammatory response
- Last line is immune response