All of Flashcards
Acetaminophen) Dynamics:
Indications:
Contra:
Dose:
= Nonopioid Analgesic/Antipyretic Fever,
= pain management
= AMS
= IV/IO: 1 gram over 10 - 15 minutes, PO: 15 mg/kg
Activated Charcoal) Dynamics:
Indications:
Contra:
Dose:
= Binds & adsorbs toxic substances in digestive tract
= Most oral poisonings/overdoses
= ↓ LOC, OD of corrosives, caustics, petroleum substances.
= PO: 1-2 g/kg
Aspirin) Dynamics:
Indications:
Contra:
Dose:
= Blocks Cyclooxygenase (enzyme body alarm). COX acts upon Arachidonic Acid which inturn gen/s Thromboxane A2, a compound that reg/s activation of platelets to form a clot.
= Cardiac signs/symptoms with ischemic etiology /suspected MI
= Allergy to medication. Bronchospasm, Angioedema.
=160-325 mg PO of nonenteric coated ASA.
Diazepam) Dynamics:
Indications:
Contra:
Dose:
= Benzodiazepine. Binds w/ GABA receptors causing an influx of Cl
= Tcardia due to stimulant OD, Substained seizures. Anxiety. Sedation.
= Hypersensitivity
= 2.5-10 mg in 2.5 mg increments slow IV/IO/IM
Droperidol) Dynamics:
Indications:
Contra:
Dose:
= Antipsychotic
= Severe agitation
= suspected QT prolongation
= 5-10 mg
Etomidate) Dynamics:
Indications:
Contra:
Dose:
= Nonbarbiturate, nonbenzodiazepine sedative Interacts w/ GABA receptors. Anesthetic w/o analgesic.
= Sedation / SFI/RSI
= Hypersensitivity
= 0.2-0.4 mg/kg (limit to 1 dose). Onset 30 secs Duration: 5-10 mins
Flumazenil) Dynamics:
Indications:
Contra:
Dose:
= Benzodiazepine Antagonist. Competitively blocks benzos @ GABA/benzo receptor complex
= Benzodiazepines OD
= Hypersensitivity
= 0.2 mg IV/IO q30 seconds max 3 mg
Haloperidol) Dynamics:
Indications:
Contra:
<69 y/o dose:
>69 y/o dose:
= Effective anxiolytic agent: blocks dopamine
receptors associated with mood & behavior
= Psychosis, chemical restraint
= Parkinson’s disease, Acute CNS injury, Hypersensitivity, <6 y/o
= <69 y/o: 5 mg IM (max 20 mg per day)
= >69 y/o: 2.5 mg IM (max 10 mg per day)
(Haloperidol/ Haldol) Indications:
Contraindications:
Others:
= Psychosis
= Known Hypersensitivity, Hypotension
= Hypotension w/ PTs taking Anti-hypertensives
Hydroxocobalamin) Dynamics:
Indications:
Contra:
Dose:
= Binds w/ cyanide to form nontoxic cyanacobalamin (Vitamin B12), preventing its toxic effects.
= Suspected cyanide poisoning
= Hypersensitivity
= 5Gs IV/O over 15 mins. May repeat 2nd 5G dose (max 10G)
Ibuprofen) Dynamics:
Indications:
Contra:
Dose:
= Anti-inflammatory & antipyretic via inhibition of prostaglandins.
= Mild - moderate pain, Fever, Inflammation.
= Hypersensitivity, Bronchospasm, Angioedema.
= 200-800 mg PO q6-8 hours, Max daily dose: 3200 mg
Ketamine) Dynamics:
Indications:
Contra:
Sedation Dose:
Pain dose:
= Dissociative anesthetic. NMDA Receptor Antagonist Anesthetic
= Sedation, SFI/RSI, Analgesic
= Hypersensitivity
= Sedation: 1-2 mg/kg Onset: 30-60 secs, Duration: 10-20 mins
= Pain: 0.2 mg/kg IV/IO (max single dose 20 mg), 0.5 mg/kg IM/IN (if no IV/IO)
Ketorolac (Toradol) Dynamics:
Indications:
Contra:
Dose:
= Anti-inflammatory & antipyretic through inhibition of prostaglandins
= Mild-moderate pain, Fever, Inflammation, Renal calculi
= Hypersensitivity, Bronchospasm, Angioedema
= 15mg IV, 30mgIM
Levalbuterol (Xopenex) Dynamics:
Indications:
Contra:
Dose:
= ß Agonist w/ preference for ß2 receptors. <effects on heart vs Albuterol.
= Bronchospasm, Allergies/anaphylaxis, Hyperkalemia
= Hypersensitivity
= 0.63 mg/3 mL via SVN
Lorazepam) Dynamics:
Indications:
Contra:
Dose:
= Benzodiazepines, Binds w/ GABA receptors causing an influx of Cl
= Sustained seizures, anxiety, sedation, chemical restraint
= Hypersensitivity
= 2-4 mg (may repeat to a max dose of 8 mg)
Methylene Blue) Dynamics:
Indications:
Contra:
Dose:
= Water soluable thiazine dye helps metHb to hemoglobin conversion
= Methemoglobinemia (metHb), Nitrate OD/poisoning
= Hypersensitivity
= 1 mg/kg IV/IO over 5-30 minutes.
Midazolam (Versed) Dynamics:
Indications:
Contra:
Seizures Dose:
RSI Dose:
= Benzodiazepine, binds w/ GABA receptors causing an influx of Cl
= Active seizures, Chemical restraint, Anxiety, RSI/SFI, Sedation
= Hypersensitivity
= 0.2 mg/kg in 2 mg increments IV/IO (max 10 mg). 5 mg IM/IN
= 0.1-0.3 mg/kg slow IV/IO (max 10 mg) Onset: 2-5 mins. Duration: 15-30 mins.
Morphine) Dynamics:
indications:
Contra:
Analgesia:
STEMI:
NSTEMI-ACS:
= Narcotic (Schedule II Opioid) Analgesia & sedation via binding to opiate receptor
= Ischemic chest pain not relieved by Nitroglycerin
= Hypersensitivity. Uncorrected hypotension (<90 SBP)
= 2-10 mg up to max 20 mg.
= 2-4mg slow IV/O, may admin 2nd dose 2-8mg IV/IO q5-15 mins
= 0.1 mg/kg slow IV/IO or IM up to 10 mg
(Propofol/ Diprivan) Class:
Dose:
= Sedative
= 1-2 mg//kg IV/IO Onset: <1min, Lasts: 5-10mins
Sodium Bicarbonate 8.4%) Dynamics:
Indications:
Contra:
Suspected acidosis Dose:
Hyperkalemia Dose:
= Alkalinizing Agent. Increases plasma bicarbonate, buffers excess hydrogen ion concertration, raises blood pH & reverses clinical manifestations of acidosis.
= Suspected hyperkalemia, suspected bicarbonateresponsive acidosis (DKA, OD on TCA’s, Aspirin or Cocaine)
= Patients in cardiac arrest
= 1 mEq/kg, Hyperkalemia:
= 50 mEq IV bolus.
Succinylcholine) Dynamics
Indications:
Contra:
Dose:
= Depolarizing neuromuscular blocker. Binds to Ach recptors
= DSI/RSI
= Hyperkalemia(burns, crush injury), Increased ICP, Severe trauma
= 1-1.5 mg/kg IV/IO. TTP: 45-60 seconds. DOP: 5-10 mins.
Tranexamic Acid (TXA) Dynamics:
Indications:
Contra:
Dose:
= Binds to plasminogen, blocking plasminogen fibrin interactions (fibrinolysis)
= Sig/ hemorrhage, either in/external (after external hemorrhage is controlled)
= SP 3 hrs past injury, allergy/Sensitivity, Suspected thromboembolism
1 gram over 10 minutes (mix in 50 mL bag of
NS), Followed by 1 gram over 8 hours (500 mL
bag NS).
Epinephrine 1:10) Dynamics:
Indications:
Contra:
Dose:
=SNS agonist. Powerful αß agonist
=Cardiac arrest, S/S bradyC.Normovolemic hypoBP, anaphylaxis
= Few in the emergency setting Benefits outweigh risks
= Cardiac arrest: 1 mg IVP/IOP q3-5
= Bradycardia: 2-10 mcg/min IV/IO infusion
= Normovolemic hypoBP & anaphylaxis: 0.1-0.5 mcg/kg/min. Mix 1mg of Epi 1:10,000 into 1L bag of fluid.
Vecuronium) Dynamics:
Indications:
Contra:
Dose:
= Nondepolarizing neuromuscular blocker Binds to ACh receptors
= DSI/RSI
= Hypersensitivity
= 0.1-0.2 mg/kg IV/IO. TTP: 1-3 mins DOP: 45-90mins
Verapamil) Dynamics:
Indications:
Contra:
Dose:
Class IV Antiarrhythmic. Slows AP of cardiac autorhythmic cells by blocking Ca channels
= 2nd line med for A-Fib & A-Flutter w/ RVR. May use as alterative med (after adenosine) narrow QRS complex tachycardia w/ preserved LV Fn
= HypoBP, CHF/Cardio shock, WPW, Wide-complex TachyC, sensitivity
=1st dose: 2.5-5 mg IV/Io bolus over 2-3 mins.
=2nd dose: 5-10 mg over 2-3 mins. Max total dose: 20 mg
Hypotensive therapy) Dynamics:
Indications:
Dose:
= giving enough fluids to get a radial pulse to perfuse
= incontrollable hemorrhage
= 20mL/Kg till radial pulse
Labetalol) Dynamics:
Indications:
Contra:
Dose:
ß Blocker thus slowing of HR
= 2nd line med for SVT after Adenosine, A-fib& flutter w/RVR, Reduce MC ischemia in AMI PT’s w/elevated HR, Antihypertensive
= Don’t administer to PT’s w/STEMI if any of the following are present: Signs of heart failure, Low cardiac output, Increased risk of cardiogenic shock. Hypotension. Bradycardia.
= 10mg IV/O push/1-2 mins. May repeat q10 mins to max of 150mg
Levalbuterol (Xopenex) Dynamics:
Indications:
Contra:
Dose:
= ß Agonist w/ preference for ß2 receptors. Has <effects on heart vs. Albuterol
=Bronchospasm, Allergies/anaphylaxis, Hyperkalemia
=Hypersensitivity
= 0.63 mg/3 mL via SVN
Etomidate) Dynamics:
Indications:
Contra:
Dose:
= Nonbarbiturate, nonbenzodiazepine sedative Interacts w/ GABA receptors
=Anesthetic w/o analgesic & Sedation / SFI/RSI
=Hypersensitivity
= 0.2-0.4 mg/kg (limit to 1 dose). Onset w/in 30 secs, Lasts: 5-10 mins