All of Flashcards
Acetaminophen) Dynamics:
Indications:
Contra:
Dose:
= Nonopioid Analgesic/Antipyretic Fever,
= pain management
= AMS
= IV/IO: 1 gram over 10 - 15 minutes, PO: 15 mg/kg
Activated Charcoal) Dynamics:
Indications:
Contra:
Dose:
= Binds & adsorbs toxic substances in digestive tract
= Most oral poisonings/overdoses
= ↓ LOC, OD of corrosives, caustics, petroleum substances.
= PO: 1-2 g/kg
Aspirin) Dynamics:
Indications:
Contra:
Dose:
= Blocks Cyclooxygenase (enzyme body alarm). COX acts upon Arachidonic Acid which inturn gen/s Thromboxane A2, a compound that reg/s activation of platelets to form a clot.
= Cardiac signs/symptoms with ischemic etiology /suspected MI
= Allergy to medication. Bronchospasm, Angioedema.
=160-325 mg PO of nonenteric coated ASA.
Diazepam) Dynamics:
Indications:
Contra:
Dose:
= Benzodiazepine. Binds w/ GABA receptors causing an influx of Cl
= Tcardia due to stimulant OD, Substained seizures. Anxiety. Sedation.
= Hypersensitivity
= 2.5-10 mg in 2.5 mg increments slow IV/IO/IM
Droperidol) Dynamics:
Indications:
Contra:
Dose:
= Antipsychotic
= Severe agitation
= suspected QT prolongation
= 5-10 mg
Etomidate) Dynamics:
Indications:
Contra:
Dose:
= Nonbarbiturate, nonbenzodiazepine sedative Interacts w/ GABA receptors. Anesthetic w/o analgesic.
= Sedation / SFI/RSI
= Hypersensitivity
= 0.2-0.4 mg/kg (limit to 1 dose). Onset 30 secs Duration: 5-10 mins
Flumazenil) Dynamics:
Indications:
Contra:
Dose:
= Benzodiazepine Antagonist. Competitively blocks benzos @ GABA/benzo receptor complex
= Benzodiazepines OD
= Hypersensitivity
= 0.2 mg IV/IO q30 seconds max 3 mg
Haloperidol) Dynamics:
Indications:
Contra:
<69 y/o dose:
>69 y/o dose:
= Effective anxiolytic agent: blocks dopamine
receptors associated with mood & behavior
= Psychosis, chemical restraint
= Parkinson’s disease, Acute CNS injury, Hypersensitivity, <6 y/o
= <69 y/o: 5 mg IM (max 20 mg per day)
= >69 y/o: 2.5 mg IM (max 10 mg per day)
Hydroxocobalamin) Dynamics:
Indications:
Contra:
Dose:
= Binds w/ cyanide to form nontoxic cyanacobalamin (Vitamin B12), preventing its toxic effects.
= Suspected cyanide poisoning
= Hypersensitivity
= 5Gs IV/O over 15 mins. May repeat 2nd 5G dose (max 10G)
Ibuprofen) Dynamics:
Indications:
Contra:
Dose:
= Anti-inflammatory & antipyretic via inhibition of prostaglandins.
= Mild - moderate pain, Fever, Inflammation.
= Hypersensitivity, Bronchospasm, Angioedema.
= 200-800 mg PO q6-8 hours, Max daily dose: 3200 mg
Ketamine) Dynamics:
Indications:
Contra:
Sedation Dose:
Pain dose:
= Dissociative anesthetic. NMDA Receptor Antagonist Anesthetic
= Sedation, SFI/RSI, Analgesic
= Hypersensitivity
= Sedation: 1-2 mg/kg Onset: 30-60 secs, Duration: 10-20 mins
= Pain: 0.2 mg/kg IV/IO (max single dose 20 mg), 0.5 mg/kg IM/IN (if no IV/IO)
Ketorolac (Toradol) Dynamics:
Indications:
Contra:
Dose:
= Anti-inflammatory & antipyretic through inhibition of prostaglandins
= Mild-moderate pain, Fever, Inflammation, Renal calculi
= Hypersensitivity, Bronchospasm, Angioedema
= 15mg IV, 30mgIM
Levalbuterol (Xopenex) Dynamics:
Indications:
Contra:
Dose:
= ß Agonist w/ preference for ß2 receptors. <effects on heart vs Albuterol.
= Bronchospasm, Allergies/anaphylaxis, Hyperkalemia
= Hypersensitivity
= 0.63 mg/3 mL via SVN
Lorazepam) Dynamics:
Indications:
Contra:
Dose:
= Benzodiazepines, Binds w/ GABA receptors causing an influx of Cl
= Sustained seizures, anxiety, sedation, chemical restraint
= Hypersensitivity
= 2-4 mg (may repeat to a max dose of 8 mg)
Methylene Blue) Dynamics:
Indications:
Contra:
Dose:
= Water soluable thiazine dye helps metHb to hemoglobin conversion
= Methemoglobinemia (metHb), Nitrate OD/poisoning
= Hypersensitivity
= 1 mg/kg IV/IO over 5-30 minutes.
Midazolam (Versed) Dynamics:
Indications:
Contra:
Seizures Dose:
RSI Dose:
= Benzodiazepine, binds w/ GABA receptors causing an influx of Cl
= Active seizures, Chemical restraint, Anxiety, RSI/SFI, Sedation
= Hypersensitivity
= 0.2 mg/kg in 2 mg increments IV/IO (max 10 mg). 5 mg IM/IN
= 0.1-0.3 mg/kg slow IV/IO (max 10 mg) Onset: 2-5 mins. Duration: 15-30 mins.
Morphine) Dynamics:
indications:
Contra:
Analgesia:
STEMI:
NSTEMI-ACS:
= Narcotic (Schedule II Opioid) Analgesia & sedation via binding to opiate receptor
= Ischemic chest pain not relieved by Nitroglycerin
= Hypersensitivity. Uncorrected hypotension (<90 SBP)
= 2-10 mg up to max 20 mg.
= 2-4mg slow IV/O, may admin 2nd dose 2-8mg IV/IO q5-15 mins
= 0.1 mg/kg slow IV/IO or IM up to 10 mg
Sodium Bicarbonate 8.4%) Dynamics:
Indications:
Contra:
Suspected acidosis Dose:
Hyperkalemia Dose:
= Alkalinizing Agent. Increases plasma bicarbonate, buffers excess hydrogen ion concertration, raises blood pH & reverses clinical manifestations of acidosis.
= Suspected hyperkalemia, suspected bicarbonateresponsive acidosis (DKA, OD on TCA’s, Aspirin or Cocaine)
= Patients in cardiac arrest
= 1 mEq/kg, Hyperkalemia:
= 50 mEq IV bolus.
Succinylcholine) Dynamics
Indications:
Contra:
Dose:
= Depolarizing neuromuscular blocker. Binds to Ach recptors
= DSI/RSI
= Hyperkalemia(burns, crush injury), Increased ICP, Severe trauma
= 1-1.5 mg/kg IV/IO. TTP: 45-60 seconds. DOP: 5-10 mins.
Lidocaine) Dynamics:
Indications:
Contra:
Dose:
= Class Ib Antiarrhythmic. Blocks Na channels in cardiac cells thus depolarization to slow and decrease in automaticity
= Alterative to Amiodarone in cardiac arrest, V-Fib/pVT Stable monomorphic Ventricular Tachycardia w/ a presserved LVF
= Should not use if PT has received IV Ca-channel blockers, Not given prophylactically in AMI setting
= VF/pVT: 1-1.5 mg/kg IV/IO, may give additional: 0.5-0.75 mg/kg IV/IO in 5-10 mins-Max 3 mg/kg
= Arrhythmia w/pulse: 1-1.5 mg/kg IV/IO, may give add: 0.5-0.75 mg/kg IV/IO in 5-10 mins-Max 3 mg/kg
= Maintenance infusion: 1-4 mg/min (30-50mcg/kg/min)
) Dynamics:
Indications:
Contra:
Dose:
Lorazepam) Dynamics:
Indications:
Contra:
Dose:
= Benzo Binds w/ GABA receptors causing an influx of Cl
= Sustained seizures, anxiety, sedation, chem restraint
= Hypersensitivity
= 2-4 mg (may repeat to a max dose of 8 mg)
Magnesium Sulfate) Dynamics:
Indications:
Contra:
Dose:
= Organic Salt act as a physiologic Ca channel blocker
= Bronchial Asthma, Torsades de Pointes (TdP) w/ or w/o a pulse, Eclampsia w/ active seizures
= Routine admin in PT’s w/AMI not recommended, High-degree HB, Shock, Dialysis, Hypocalcemia, V-fib/pulseless V-Tach,
= Respriatory: 1-2 grams IV/IO over 10-20 minutes
Tdp w/pulse: 1-2 grams mixed in 50-100 mL over 5-60 minutes
Cardiac arrest due to hypomagnesemia or TdP: 1-2 grams in 10 mL
Eclampsia: 1-4 grams
Methylene Blue) Dynamics:
Indications:
Contra:
Dose:
= H20 soluable thiazine dye promotes converting metHb>hemoglobin
= Methemoglobinemia (metHb), Nitrate overdose/poisoning = Hypersensitivity
= 1 mg/kg IV/IO over 5-30 mins
Metoprolol) Dynamics:
Indications:
Contra:
Dose:
= ß-Blocker
= Hypertension, 2nd line med for A-Fib or A-Flutter w/ RVR, & SVT
= HR<45, 2nd or 3rd degree heart block
= 5 mg IV/IO q 5 min (up to 3 doses)
Midazolam) Dynamics:
Indications:
Contra:
Dose:
= Benzo binds w/ GABA receptors causing an influx of Cl
= Active seizures, Chem restraint, Anxiety, Induct RSI/SFI), Sedation
= Hypersensitivity
= Seizures: 0.2 mg/kg in 2 mg increments IV/IO (max 10 mg)
= RSI: .1-0.3 mg/kg IV/O (max 10mg)Onset: 2-5 mins, Last: 15-30 mins.
Morphine) Dynamics:
Indications:
Contra:
Dose:
Narcotic (Schedule II Opioid). Analgesia & sedation w/ binding to opiate receptor
= Ischemic chest pain not relieved by Nitro
= Hypersensitivity. Uncorrected SBP<90
= Analgesia: 2-10 mg up to max 20 mg
STEMI: 2-4 mg slow IV/IO, may admin 2nd dose of 2-8 mg IV/IO q5-15 mins intervals
NSTEMI-ACS: 0.1mg/kg slow IV/IO or IM up to 10 mg.
Naloxone (Narcan) Dynamics:
Indications:
Contra:
Dose:
= Opiate Competitive Antagonist
= Suspected Opiate overdose w/ respiratory depression
= Hypersensitivity
= 0.4-2 mg IV/IO/IM/IN
Nitroglycerin) Dynamics:
Indications:
Contra:
Dose:
= Nitrate. Potent vasodilator opens coronary vessels to improve blood flow to the myocardium & <overall workload of the heart & afterload.
= Symptoms suggest MI (farc/schem), CHF, SBP<90, <50 BPM
= >100 BPM, RVI, Use of phosphodiesterase inhibitors (Boner Pills) last 48hours), Increased ICP
=0.4 mg tablet or spray - repeat X 3 (q5mins) for total max dose 1.2 mg. Do not shake aerosol spray because this affects the metered dose
Norepinephrine) Dynamics:
Indications:
Contra:
Dose:
= αß adrenergic agonist (α > ß effects)
= Normovolemic hypoBP, Sepsis, Cardiogenic shock
= Shouldn’t use in hypovol/ til’ vol/ replacement occurred
= 0.1-0.5 mcg/kg/min IV/IO infusion