All of Flashcards

(116 cards)

1
Q

Acetaminophen) Dynamics:
Indications:
Contra:
Dose:

A

= Nonopioid Analgesic/Antipyretic Fever,
= pain management
= AMS
= IV/IO: 1 gram over 10 - 15 minutes, PO: 15 mg/kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Activated Charcoal) Dynamics:
Indications:
Contra:
Dose:

A

= Binds & adsorbs toxic substances in digestive tract
= Most oral poisonings/overdoses
= ↓ LOC, OD of corrosives, caustics, petroleum substances.
= PO: 1-2 g/kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Aspirin) Dynamics:

Indications:
Contra:
Dose:

A

= Blocks Cyclooxygenase (enzyme body alarm). COX acts upon Arachidonic Acid which inturn gen/s Thromboxane A2, a compound that reg/s activation of platelets to form a clot.
= Cardiac signs/symptoms with ischemic etiology /suspected MI
= Allergy to medication. Bronchospasm, Angioedema.
=160-325 mg PO of nonenteric coated ASA.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Diazepam/Vallium) Dynamics:
Indications:
Contra:
Dose:

A

= Benzodiazepine. Binds w/ GABA receptors causing an influx of Cl
= Tcardia due to stimulant OD, Substained seizures. Anxiety. Sedation.
= Hypersensitivity
= 2.5-10 mg in 2.5 mg increments slow IV/IO/IM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Droperidol) Dynamics:
Indications:
Contra:
Dose:

A

= Antipsychotic
= Severe agitation
= suspected QT prolongation
= 5-10 mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Etomidate) Dynamics:

Indications:
Contra:
Dose:

A

= Nonbarbiturate, nonbenzodiazepine sedative Interacts w/ GABA receptors. Anesthetic w/o analgesic.
= Sedation / SFI/RSI
= Hypersensitivity
= 0.2-0.4 mg/kg (limit to 1 dose). Onset 30 secs Duration: 5-10 mins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Flumazenil) Dynamics:

Indications:
Contra:
Dose:

A

= Benzodiazepine Antagonist. Competitively blocks benzos @ GABA/benzo receptor complex
= Benzodiazepines OD
= Hypersensitivity
= 0.2 mg IV/IO q30 seconds max 3 mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Haloperidol) Dynamics:

Indications:
Contra:
<69 y/o dose:
>69 y/o dose:

A

= Effective anxiolytic agent: blocks dopamine
receptors associated with mood & behavior
= Psychosis, chemical restraint
= Parkinson’s disease, Acute CNS injury, Hypersensitivity, <6 y/o
= <69 y/o: 5 mg IM (max 20 mg per day)
= >69 y/o: 2.5 mg IM (max 10 mg per day)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Haloperidol/ Haldol) Indications:
Contraindications:
Others:

A

= Psychosis
= Known Hypersensitivity, Hypotension
= Hypotension w/ PTs taking Anti-hypertensives

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Hydroxocobalamin) Dynamics:

Indications:
Contra:
Dose:

A

= Binds w/ cyanide to form nontoxic cyanacobalamin (Vitamin B12), preventing its toxic effects.
= Suspected cyanide poisoning
= Hypersensitivity
= 5Gs IV/O over 15 mins. May repeat 2nd 5G dose (max 10G)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Ibuprofen) Dynamics:
Indications:
Contra:
Dose:

A

= Anti-inflammatory & antipyretic via inhibition of prostaglandins.
= Mild - moderate pain, Fever, Inflammation.
= Hypersensitivity, Bronchospasm, Angioedema.
= 200-800 mg PO q6-8 hours, Max daily dose: 3200 mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Ketamine) Dynamics:
Indications:
Contra:
Sedation Dose:
Pain dose:

A

= Dissociative anesthetic. NMDA Receptor Antagonist Anesthetic
= Sedation, SFI/RSI, Analgesic
= Hypersensitivity
= Sedation: 1-2 mg/kg Onset: 30-60 secs, Duration: 10-20 mins
= Pain: 0.2 mg/kg IV/IO (max single dose 20 mg), 0.5 mg/kg IM/IN (if no IV/IO)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Ketorolac (Toradol) Dynamics:
Indications:
Contra:
Dose:

A

= Anti-inflammatory & antipyretic through inhibition of prostaglandins
= Mild-moderate pain, Fever, Inflammation, Renal calculi
= Hypersensitivity, Bronchospasm, Angioedema
= 15mg IV, 30mgIM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Levalbuterol (Xopenex) Dynamics:

Indications:
Contra:
Dose:

A

= ß Agonist w/ preference for ß2 receptors. <effects on heart vs Albuterol.
= Bronchospasm, Allergies/anaphylaxis, Hyperkalemia
= Hypersensitivity
= 0.63 mg/3 mL via SVN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Lorazepam/ Ativan) Dynamics:
Indications:
Contra:
Dose:

A

= Benzodiazepines, Binds w/ GABA receptors causing an influx of Cl
= Sustained seizures, anxiety, sedation, chemical restraint
= Hypersensitivity
= 2-4 mg (may repeat to a max dose of 8 mg)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Methylene Blue) Dynamics:
Indications:
Contra:
Dose:

A

= Water soluable thiazine dye helps metHb to hemoglobin conversion
= Methemoglobinemia (metHb), Nitrate OD/poisoning
= Hypersensitivity
= 1 mg/kg IV/IO over 5-30 minutes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Midazolam (Versed) Dynamics:
Indications:
Contra:
Seizures Dose:
RSI Dose:

A

= Benzodiazepine, binds w/ GABA receptors causing an influx of Cl
= Active seizures, Chemical restraint, Anxiety, RSI/SFI, Sedation
= Hypersensitivity
= 0.2 mg/kg in 2 mg increments IV/IO (max 10 mg). 5 mg IM/IN
= 0.1-0.3 mg/kg slow IV/IO (max 10 mg) Onset: 2-5 mins. Duration: 15-30 mins.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Morphine) Dynamics:

indications:
Contra:
Analgesia:
STEMI:
NSTEMI-ACS:

A

= Narcotic (Schedule II Opioid) Analgesia & sedation via binding to opiate receptor
= Ischemic chest pain not relieved by Nitroglycerin
= Hypersensitivity. Uncorrected hypotension (<90 SBP)
= 2-10 mg up to max 20 mg.
= 2-4mg slow IV/O, may admin 2nd dose 2-8mg IV/IO q5-15 mins
= 0.1 mg/kg slow IV/IO or IM up to 10 mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

(Propofol/ Diprivan) Class:
Dose:

A

= Sedative
= 1-2 mg//kg IV/IO Onset: <1min, Lasts: 5-10mins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Sodium Bicarbonate 8.4%) Dynamics:

Indications:

Contra:
Suspected acidosis Dose:
Hyperkalemia Dose:

A

= Alkalinizing Agent. Increases plasma bicarbonate, buffers excess hydrogen ion concertration, raises blood pH & reverses clinical manifestations of acidosis.
= Suspected hyperkalemia, suspected bicarbonateresponsive acidosis (DKA, OD on TCA’s, Aspirin or Cocaine)
= Patients in cardiac arrest
= 1 mEq/kg, Hyperkalemia:
= 50 mEq IV bolus.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Succinylcholine) Dynamics
Indications:
Contra:
Dose:

A

= Depolarizing neuromuscular blocker. Binds to Ach recptors
= DSI/RSI
= Hyperkalemia(burns, crush injury), Increased ICP, Severe trauma
= 1-1.5 mg/kg IV/IO. TTP: 45-60 seconds. DOP: 5-10 mins.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Epinephrine 1:10) Dynamics:
Indications:
Contra:
Dose:

A

=SNS agonist. Powerful αß agonist
=Cardiac arrest, S/S bradyC.Normovolemic hypoBP, anaphylaxis
= Few in the emergency setting Benefits outweigh risks
= Cardiac arrest: 1 mg IVP/IOP q3-5
= Bradycardia: 2-10 mcg/min IV/IO infusion
= Normovolemic hypoBP & anaphylaxis: 0.1-0.5 mcg/kg/min. Mix 1mg of Epi 1:10,000 into 1L bag of fluid.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Tranexamic Acid (TXA) Dynamics:
Indications:
Contra:
Dose:

A

= Binds to plasminogen, blocking plasminogen fibrin interactions (fibrinolysis)
= Sig/ hemorrhage, either in/external (after external hemorrhage is controlled)
= SP 3 hrs past injury, allergy/Sensitivity, Suspected thromboembolism
1 gram over 10 minutes (mix in 50 mL bag of
NS), Followed by 1 gram over 8 hours (500 mL
bag NS).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Vecuronium) Dynamics:
Indications:
Contra:
Dose:

A

= Nondepolarizing neuromuscular blocker Binds to ACh receptors
= DSI/RSI
= Hypersensitivity
= 0.1-0.2 mg/kg IV/IO. TTP: 1-3 mins DOP: 45-90mins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Verapamil) Dynamics: Indications: Contra: Dose:
Class IV Antiarrhythmic. Slows AP of cardiac autorhythmic cells by blocking Ca channels = 2nd line med for A-Fib & A-Flutter w/ RVR. May use as alterative med (after adenosine) narrow QRS complex tachycardia w/ preserved LV Fn = HypoBP, CHF/Cardio shock, WPW, Wide-complex TachyC, sensitivity =1st dose: 2.5-5 mg IV/Io bolus over 2-3 mins. =2nd dose: 5-10 mg over 2-3 mins. Max total dose: 20 mg
26
Hypotensive therapy) Dynamics: Indications: Normovelmic Dose:
= giving enough fluids to get a radial pulse to perfuse = incontrollable hemorrhage = 20mL/Kg till radial pulse
27
Labetalol) Dynamics: Indications: Contra: Dose:
ß Blocker thus slowing of HR = 2nd line med for SVT after Adenosine, A-fib& flutter w/RVR, Reduce MC ischemia in AMI PT's w/elevated HR, Antihypertensive = Don't administer to PT's w/STEMI if any of the following are present: Signs of heart failure, Low cardiac output, Increased risk of cardiogenic shock. Hypotension. Bradycardia. = 10mg IV/O push/1-2 mins. May repeat q10 mins to max of 150mg
28
Levalbuterol (Xopenex) Dynamics: Indications: Contra: Dose:
= ß Agonist w/ preference for ß2 receptors. Has
29
Etomidate) Dynamics: Indications: Contra: Dose:
= Nonbarbiturate, nonbenzodiazepine sedative Interacts w/ GABA receptors =Anesthetic w/o analgesic & Sedation / SFI/RSI =Hypersensitivity = 0.2-0.4 mg/kg (limit to 1 dose). Onset w/in 30 secs, Lasts: 5-10 mins
30
Fentanyl) Dynamics: Indications: Contra: Dose:
=Synthetic Narcotic (Schedule II Opioid) = Analgesia & sedation via binding to opiate receptor, sig/ more potent than morphine (100 mcg = 10 mg of Morphine) = Moderate-Severe pain = Hypersensitivity, SBP<90 =1mcg/kg to a max dose 100 mcg (IV/IO/IM/) may repeat PRN in 5-10 = 1mcg/kg IN may repeat PRN 5-10mins (Max 1mL PRN if admin/ed IN)
31
Flumazenil) Dynamics: Indications: Contra: Dose:
= Benzodiazepine Antagonist = Competitively blocks benzos @ GABA/benzo receptor complex = Benzodiazepines overdose = Hypersensitivity = 0.2 mg IV/IO q30 seconds Max up to 3 mg total dose
32
Furosemide) Dynamics: Indications: Contra: Dose:
= Loop-Diuretic stops Na,Cl,&H2O from kidney tubules thus +urine = Acute pulmonary edema in PTs w/ SBP>90-100 (w/o signs of shock), Hypertensive emergencies. = Hypovol, HypoBP, HypoK or other pos/ electrolyte abnormalities = 1st: 0.5-1 mg/kg/ 1-2 mins, 2nd: double 1st dose to 2 mg/kg/1-2 mins Acute pulmonary edema w/ suspected hypovol:<0.5 mg/kg slow IV.
33
Glucagon) Dynamics: Indications: Contra: Dose:
= Hormone Binds to Glucagon receptors & stim/s adenyal clyclase, thus +cAMP which up-regulation of Ca cAMP channels in SA & AV cells = Hypoglycemia, BradyC suspected from ßeta/Ca channel blocker OD = Hypersensitivity, Bradycardia from other etiology =Hypoglycemia: 1 mg IM. =BradyC suspected from ßeta/Ca channel blocker OD: 3-10 mg IV/3-5 mins Followed by an infusion of 3-5 mg per Hr
34
Haloperidol ) Dynamics: Indications: Contra: Dose:
= Effective anxiolytic agent: blocks dopamine receptors associated w/ mood & behavior =Psychosis, chem restraint = Parkinson's disease, Acute CNS injury, Hypersensitivity, <6 y/o = <69 y/o: 5 mg IM (max 20 mg per day) = >69 y/o: 2.5 mg IM (max 10 mg per day)
35
Hydroxocobalamin) Dynamics: Indications: Contra: Dose:
Binds with cyanide to form nontoxic cyanacobalamin (Vitamin B12), preventing its toxic effects. Suspected cyanide poisoning Hypersensitivity 5 grams IV/IO over 15 minutes. May repeat a 2nd 5 gram dose for a max of 10 grams
36
Ibuprofen) Dynamics: Indications: Contra: Dose:
= Anti-inflammatory & antipyretic via inhibition of prostaglandins. = Mild-moderate pain, Fever, Inflammation. =Hypersensitivity, Bronchospasm, Angioedema. = 200-800 mg PO q6-8 hours, Max daily dose:3200 mg
37
Ipratropium (Atrovent) Dynamics: Indications: Contra: Dose:
= Anticholinergic. Selectively blocks musarinic receptors. = Bronchospasm associated w/ obstructive lung diseases =Hypersensitivity = 500 mcg/2.5 mL via SVN
38
Ketorolac (Toradol) Dynamics: Indications: Contra: Dose:
= Anti-inflammatory & antipyretic via inhibition of prostaglandins. = Mild-moderate pain, Fever, Inflammation, Renal calculi. = Hypersensitivity, Bronchospasm, Angioedema = 15 mg IV 30 mg IM
39
Ketamine) Dynamics: Indications: Contra: Dose:
= Dissociative anesthetic. NMDA Receptor Antagonist =Anesthetic Sedation / SFI/RSI / = Hypersensitivity = Sedation: 1-2 mg/kg Onset: 30-60 secs, Lasts: 10-20 mins = Analgesia/Pain: 0.2 mg/kg IV/IO (max single dose 20 mg), 0.5 mg/kg IM/IN (if no IV/IO)
40
Methylene Blue) Dynamics: Indications: Contra: Dose:
= H20 soluable thiazine dye promotes converting metHb>hemoglobin = Methemoglobinemia (metHb), Nitrate overdose/poisoning = Hypersensitivity = 1 mg/kg IV/IO over 5-30 mins
41
Lidocaine) Dynamics: Indications: Contra: Dose:
= Class Ib Antiarrhythmic. Blocks Na channels in cardiac cells thus depolarization to slow and decrease in automaticity = Alterative to Amiodarone in cardiac arrest, V-Fib/pVT Stable monomorphic Ventricular Tachycardia w/ a presserved LVF = Should not use if PT has received IV Ca-channel blockers, Not given prophylactically in AMI setting = VF/pVT: 1-1.5 mg/kg IV/IO, may give additional: 0.5-0.75 mg/kg IV/IO in 5-10 mins-Max 3 mg/kg = Arrhythmia w/pulse: 1-1.5 mg/kg IV/IO, may give add: 0.5-0.75 mg/kg IV/IO in 5-10 mins-Max 3 mg/kg = Maintenance infusion: 1-4 mg/min (30-50mcg/kg/min)
42
Magnesium Sulfate) Dynamics: Indications: Contra: Dose:
= Organic Salt act as a physiologic Ca channel blocker = Bronchial Asthma, Torsades de Pointes (TdP) w/ or w/o a pulse, Eclampsia w/ active seizures = Routine admin in PT's w/AMI not recommended, High-degree HB, Shock, Dialysis, Hypocalcemia, V-fib/pulseless V-Tach, = Respriatory: 1-2 grams IV/IO over 10-20 minutes Tdp w/pulse: 1-2 grams mixed in 50-100 mL over 5-60 minutes Cardiac arrest due to hypomagnesemia or TdP: 1-2 grams in 10 mL Eclampsia: 1-4 grams
43
Thiamine) Dynamics: Indications: Contra: Dose:
= Vitamin B1 Forms thiamine pyrophosphate by combining w/ ATP, an essential coenzyme for carbohydrate metabolism = Coma of unknown orgin, Wernicke's encephalopathy, Delirium tremens =Hypersensitivity = 100 mg IV/IO/IM
44
Metoprolol) Dynamics: Indications: Contra: Dose:
= ß-Blocker = Hypertension, 2nd line med for A-Fib or A-Flutter w/ RVR, & SVT = HR<45, 2nd or 3rd degree heart block = 5 mg IV/IO q 5 min (up to 3 doses)
45
Midazolam/Versed) Dynamics: Indications: Contra: Dose:
= Benzo binds w/ GABA receptors causing an influx of Cl = Active seizures, Chem restraint, Anxiety, Induct RSI/SFI), Sedation = Hypersensitivity = Seizures: 0.2 mg/kg in 2 mg increments IV/IO (max 10 mg) = RSI: .1-0.3 mg/kg IV/O (max 10mg)Onset: 2-5 mins, Last: 15-30 mins.
46
Morphine) Dynamics: Indications: Contra: Dose:
Narcotic (Schedule II Opioid). Analgesia & sedation w/ binding to opiate receptor = Ischemic chest pain not relieved by Nitro = Hypersensitivity. Uncorrected SBP<90 = Analgesia: 2-10 mg up to max 20 mg STEMI: 2-4 mg slow IV/IO, may admin 2nd dose of 2-8 mg IV/IO q5-15 mins intervals NSTEMI-ACS: 0.1mg/kg slow IV/IO or IM up to 10 mg.
47
Naloxone (Narcan) Dynamics: Indications: Contra: Dose:
= Opiate Competitive Antagonist = Suspected Opiate overdose w/ respiratory depression = Hypersensitivity = 0.4-2 mg IV/IO/IM/IN
48
Nitroglycerin) Dynamics: Indications: Contra: Dose:
= Nitrate. Potent vasodilator opens coronary vessels to improve blood flow to the myocardium & 100 BPM, RVI, Use of phosphodiesterase inhibitors (Boner Pills) last 48hours), Increased ICP =0.4 mg tablet or spray - repeat X 3 (q5mins) for total max dose 1.2 mg. *Do not shake aerosol spray because this affects the metered dose*
49
Ondansetron (Zofran) Dynamics: Indications: Contra: Dose:
= Selective serotonin 5-HT3 receptor blocker = Prevention & control of Nausea and/or vomiting = Hypersensitivity = 4-8 mg IV slow push, IM, PO.
50
Terbutaline (Brethine) Dynamics: Indications: Contra: Dose:
= ß2Agonist, reliefs bronchospasm,
51
Succinylcholine) Dynamics: Indications: Contra: Dose:
= Depolarizing neuromuscular blocker. Binds to Ach recptors = DSI/RSI = Hyperkalemia(burns, crush injury), +ICP, Severe trauma, Neuromuscular disease. = 1-1.5 mg/kg IV/IO. TTP: 45-60 seconds. DOP: 5-10 minutes.
52
Solu-Medrol ) Dynamics: Indications: Contra: Dose:
= Anti-inflammatory; suppresses immune response = Bronchial asthma, COPD, Anaphylaxis = Hypersensitivity = 125-250 mg IV/IO
53
Sodium Bicarbonate 8.4%) Dynamics: Indications: Contra: Dose:
= Alkalinizing Agent +plasma bicarbonate, buffers excess hydrogen ion concertration, raises blood pH & reverses manifestations of acidosis. = Suspected hyperkalemia, suspected bicarbonate responsive acidosis (DKA, OD on TCA's, Aspirin or Cocaine) = Patients in cardiac arrest = Suspected acidosis:1 mEq/kg =Hyperkalemia: 50 mEq IV bolus.
54
Racemic Epi ) Dynamics: Indications: Contra: Dose:
= Nonselective ß sympathetic agonist =Croup =Hypersensitivity =0.25-0.75 mL of a 2.25% solution diluted in 3mL of NS
55
Nubain) Dynamics: Indications: Contra: Dose:
Synthetic opiate agonist/antagonist = Moderate to severe pain = Hypersensitivity, respiratory depression = 10-20 mg IV/IO/SQ/IM
56
Procainamide) Dynamics: Indications: Contra: Dose:
=Class Ia Antiarrhythmic Blocks Na channels in cardiac cells thus slower depolarization &
57
Promethazine (Phenergan) Dynamics: Indications: Contra: Dose:
=Antiemetic. H1-receptor blocker =Nausea & Vomitinf, Peroperative sediation, motion sickness. = Hypersensitivity, Respiratory diseases(Asthma), Pedi <2 y/o = IV/IM: 12.5-25 mg, May cause tissue injury if IV extravasation.
58
Norepinephrine) Dynamics: Indications: Contra: Dose:
= αß adrenergic agonist (α > ß effects) = Normovolemic hypoBP, Sepsis, Cardiogenic shock = Shouldn't use in hypovol/ til' vol/ replacement occurred = 0.1-0.5 mcg/kg/min IV/IO infusion
59
Promethazine/Phenergan) Dynamics: Indications: Contra: Dose:
=Antiemetic. H1-receptor blocker =Nausea & Vomitinf, Peroperative sediation, motion sickness. = Hypersensitivity, Respiratory diseases(Asthma), Pedi <2 y/o = IV/IM: 12.5-25 mg, May cause tissue injury if IV extravasation.
60
Adenosine & Digoxin class
class misc
61
Adenosine) indications: contraindications
= 1st for stable narrow complex SVT, Regular & monomorphic wide-complex Tcardia thought from a reentry SVT (SVT w/ BBB) = Torsades de pointes, Poison/drug-Tcardia, 2nd or 3rd AVB, WPW,DOESNT CONVERT A-FIB/FLUTTER
62
Adenosine) class: Dynamics:
= Misc antiarrhythmic binds to adenosine A1 receptors causes efflux of K & inhibits Ca influx (in autoarhythmic cells) = Causes hyperpolarization of autorhythmic cells (SA/AV node) Slows AV conduction w/ very short half-life
63
Adenosine) Effects: Dose: admin notes:
= periods of sinus Bcardia/asystole & ventricular ectopy after admin = 1st dose 6mg rapid IV/IO push followed w/ rapid flush &2nd dose 12mg also rapid push & flush = rapid push followed by rapid flush 20mL fluid best accomplished w/ 3-way stopcock & 1/2 initial dose in PTs receiving dipyridamole or carbamazepine, heart transplant, or if given by central venous access
64
Albuterol) Dynamics: Indications: Contraindications:
=B agonist w/ preference of B2 receptors =Brocospasm, Anaphylaxsis/ asthma/ Allergies, Hyperkalemia = jitters & Known hypersensitivity
65
Albuterol) Adverse effects: Adult Broncospasm dose: Hyperkalemic dose: Pedi Dose:
= Palp/s, Anxiety, Jitters, Dizzy, Tcardia = 2.5mg/3mg via SVN→ repeat 15-20mins as needed = 10-20mg via LVN over 15 mins→ repeat as needed = 1.25-2.5mg/1.5-3mL SVN
66
Amiodarone class & indication
Class 3 K channel blocker> VF/Pulseless VT unresponsive to shock, CPR & Epi, BradyCs to include AV blocks, Recurrent, hemodynamically unstable VT w/ pulse
67
Amiodarone) Max total dose per day: Slow Infusion dose: Maintenance Infusion dose: VF/Pulseless & VT Cardiac Arrest Unresponsive 1st Dosage: VF/Pulseless & VT Cardiac Arrest Unresponsive 2nd Dosage: Life-Threatening Arrhythmia 1st Dosage: Life-Threatening Arrhythmia 2nd Dosage:
= 2.2 grams = 360 mg IV 6Hrs (1mg/min) = 540 mg IV 18Hrs (0.5 mg/min) = 300 mg IV/O push = 150 mg IV/O push if needed = 1st Dose: Rapid Infusion 150 mg/10 mins (15 mg/min) = 2nd Dose: 150mg/10 mins (15 mg/min) if needed
68
Amiodarone) Class: Dynamics: Indi: B/c its toxicity indi: W/ expert consultation may be used for: Terminal elimination:
= Class III antiarrhythmic = Slows K+ efflux delaying repolarization on all of heart = VF/Pulseless VT-no/response to shock CPR & Epi, Recurrent hemodynamically unstable VT w/ pulse = PT w/ life-threatening arrhythmias w/ monitoring = some atrial & ventricular rhythms w/ life-threatening hypoBP = Extremely long (half-life lasts max 40 days)
69
Amiodarone) Contra: Effects: Caution b/c:
= Allergic, Bradycardias w/ AV blocks, Breastfeeding mothers = Severe hypotension, Bradycardia, Prolong QT which can lead to TdP = Toxicity, Causes severe BP drop, Prolong QT which can lead to TdP
70
Antiarrhythmics for pVT, TdP, VF
pVT/ TdP= Lidocaine & Aminodarone Tdp= Mag-Sulfate
71
Aspirin) indications: Contraindications:
= Cardiac S/S w/ ischemia etiology = common allergy, Bronchospasm, Angiodema
72
Aspirin) effects: Avoid: dose:
=Can cause bromchoconstriction in ~10% asthmatic PTs, N/V, upset GI = enteric-coated Aspirin when admin/ing to PT w/ cardiac S/S = 160-325mg PO of non-entric coated ASA
73
Aspirin) Class: Dynamics:
= NSAID & COX inhibiter = Blocks cyclooxygenase (enzyme that’s basically alarm bell for body) COX acts upon Arachidonic Acid which in turn gen/s Thromboxane A2, a compound that reg/s the activation of platelets to form a clot
74
Atropine) class: Dynamics:
= parasympatholytic = selectively blocks muscarinic receptors inhibiting the parasympathetic NS “Vagus N. Blocker”- letting sympathetic take over
75
Atropine) indications: Contraindications: Avoid:
= 1st med/ for symptomatic sinus Bcardia, Maybe beneficial AV block, Organophosphate poisoning (large dose r/q) hypothermic Bcardia = Allergic to drug, Use w/ extreme caution w/ myocardial ischemia = causes increased myocardial O2 demand so caution w/ Hblock & Doses <0.5mg may result in paradoxical slowing of the heart May not be effective for infranodal blocks- be prepared to pace
76
Atropine) Adverse effects: Bradycardia (w/ or w/o ACS) Dosage: severe clinical conditions dosage: organophosphate poisoning dosage:
= Blurred vision, Dry mouth, Dilated pupils, Confusion =1 mg IV push every 3-5mins as needed (0.04mg/Kg (total 3mg) =1 mg IVP every 3 mins = 2-4mg (or higher) IVP
77
L)
78
Cardioversion/vert) Indication Rhythms intial & after Doses:
= UNSTABLE} SBP <90 & AMS = Bradycardia, AF w/ SVR, = 50-100J then 200J 300J 360J
79
Defib) indication Contra: Rhythms Initial & after doses:
= "Dead fibers" TdP (only rhythm defib awake) = Asystole VT w/ Pulse stable = pVT, VF, TdP = 100J 200J 300J 360J
80
Dexamethasone) Dynamics: Indications: Contra: Dose:
Dexamethasone Anti-inflammatory: supresses immune response Anaphylaxis, Bronchial asthma, COPD Hypersensitivity, Fungal infection 10 mg IV/IO/PO
81
Dextrose 50%) Dynamics: Indications: Contra: Dose:
Dextrose 50% Electrolyte / Carbohydrate. Water-soluble monosaccharide Correction of hypoglycemia Known hyperglycemia D50: 25 grams IV/IO, D10 in 50 mL (5 grams) IV/IO boluses (max 250 mL)
82
Diazepam) Dynamics: Indications: Contra: Dose:
= Benzodiazepine Binds with GABA receptors causing an influx of Cl = TachyC from stimulant OD, Sustained seizure, Anxiety, Sedation, = Hypersensitivity = 2.5-10 mg in 2.5 mg increments slow IV/IO/IM.
83
Diltiazem) Dynamics: Indications: Contra: Dose:
= Class IV Antiarrhythmic (Calcium Channel Blocker). Slows action potential of autorhythmic cells in the heart by blocking calcium channels. = 1st line med for A-Fib & A-Flutter with RVR (>150 bpm)2nd line med for SVT that is refractory to adenosine. = SBP<90, CHF/Cardio shock, Wide-complex TachyC, WPW, sensitivity = 1st dose: 0.25 mg/kg (max 20mg) & 2nd: 0.35 mg/kg (max 25mg)
84
Diphenhydramine) Dynamics: Indications: Contra: Dose:
= H1&2 Histamine Blocker = Allergic reaction, anaphylaxis, extrapyramidal reactions, sedation = Hypersnesitivity = 25-50 mg slow IV/IO or IM
85
Dobutamine) Dynamics: Indications: Contra: Dose:
= αß agonist. Inotropic prop/s > prounced vs chronotropic =Cardiac pump problems (CHF) w/ hypoBP, Shouldn't use in =hypovol/ til fluid replacemed. Never mix w/ Na-Bicarb. = 2-20 mcg/kg/min - titrate so heart rate does not increase by >10% of baseline.
86
Dopamine) class: pharmacodynamics
= sympathetic agonist = A/B agonist rate dependent vasopressor +chron/in/Drom/otropic
87
Dopamine) indications: Contraindications:
= CHF, HypoBP w/ shock signs, 2nd med for sympathetic Bcardia (after Atropine) = hypovolemic PTs til' vol/ replaced, pheochromocytoma, Dont mix w/ sodium bicarb
88
Dopamine) Effects: Dosing: Adult & Pedi Cardiac dose: Adult & Pedi Vasopressor dose:
= HyperBP, Palp/s, H/A, Dizzy, Can worsen C-ischemia, necrosis W/ Extravasation = 2–20 mcg/kg/min Titrate to response = 5-10mcg/kg/min = 10-20 mcg/kg/min
89
Dopamine) Dynamics: Indications: Contra: Dose:
= α & ß agonist, Rate dependent, vasopressor, +Chron/In/Dromotropic = CHF, hypoBP w/ shock S/S, 2nd med w/ S/S bradyC (after atropine) = Shouldn't use in hypovolemic PTs til' appropriate vol/ replacement occurred, Known Hx Pheochromocytoma, Don't mix w/ Sodium Bicarb. 2 - 20 mcg/kg/min, titrate to PT response (DO NOT OPEN WIDE OPEN)
90
Droperidol) Dynamics: Indications: Contra: Dose:
= Antipsychotic = Severe agitation = suspected QT prolongation = 5-10 mg
91
Enalapril) Dynamics: Indications: Contra: Dose:
ACE Inhibitor Prevents making of angiotensin II by inhibiting (ACE) thus vasodilation & helps reduce amount of water held back by the kidneys = Severe CHF (W/ HTN) in conjunction w/ Nitrates & CPAP. = Pregnancy, Angioedema, Hypersensitivity to ACE inhibitors = Pregnancy or Angioedema Initial dose of 2.5 mg PO = Sensitivity to ACE inhibitors; Titrate20mg PO(1st dose 2.5mg PO)
92
Epinephrine 1:1) Dynamics: Indications: Contra: Dose:
= Potent α and ß agonist =Severe bronchospasm, Allergies/anaphylaxis =Few, Benefits vs. risk = 0.01 mg/kg IM (max 0.3 mg)
93
L)
94
L)
95
L)
96
L)
97
L)
98
L)
99
L)
100
L)
101
Labetalol) class: pharmacodynamics:
= beta-blocker = Blocks adrenergic stim/ on B-receptors, causing a slowing of HR
102
Labetalol) Indications: Contraindications: Do not administer to PTs w/ STEMI if following present:
= 2nd med/ for SVT after admin/ Adenosine, A-Fib/Flutter w/ RVR Reduce myocardial ischemia in AMI PTs w/ +HRs, Antihypertensive = Increased risk of cardiogenic shock Hypotension Bradycardia = signs of heart failure Low cardiac output
103
Labetalol) Adverse Effects: Max dose: Adult Dose:
= admin/ after IV Ca-channel blockers can cause severe hypotension, Bcardia, heart blocks & CHF = 150mg = 10 mg IV/O push 1-2 mins & May repeat every 10 mins to max dose
104
Monophasic monitor Jules max Biphasic monitor Jules max
360J 200J
105
Nubain) Dynamics: Indications: Contra: Dose:
= Synthetic opiate agonist/antagonist = Moderate to severe pain = Hypersensitivity, respiratory depression. = 10-20 mg IV/IO/SQ/IM
106
Pacing) indication Rhythms Initial & after:
= "pick up the pace" <50BPM UNSTSBLE} SBP <90 & AMS = BPM <50 = 80BPM mA till' capture
107
Procainamide & Lidocaine) class
= class 1A&B Na Channel Blockers = Alterative to Amiodarone in cardiac arrest V-Fib/pVT, Stable monomorphic Ventricular TachyC w/ presserved LVF = V-Tach with a pulse, pre-excitation rhythms (WPW) >50% QRS width
108
(Procainamide)class: Dynamics:
= 1a antiarrhythmic = Blocks Na channels in cardiac cells which causes depolarization to slow & decrease automaticity
109
(Procainamide) indications: Contra:
=V-Tach w/ pulse, Pre-excitation rhythms (WPW) =Shouldn’t admin to PTs received IV Ca channel blocker
110
Procainamide) max dose: Recurrent VF/VT: Urgent situations: Maintenance Infusion:
= (max total dose: 17mg/kg) = 20mg/min (max total dose: 17mg/kg) = up to 50mg/min may admin/ to total dose (max 17mg/kg) = 1-4mg/min
111
Procainamide)effect: 4 ending points:
= Drowsy, Slurred speech, Confusion, Seizures, HypoBP = 1. Termination of rhythm, 2. HypoBP, 3. Widening QRS>50%, 4. Meet the max total dose
112
Propranolol, Labetalol, Metoprolol) class Labetalol Metoprolol
= class 2 Beta Blockers = 2nd line med for SVT after Adenosine, A-fib/flutter w/RVR, Reduce myocardical ischemia in AMI PT's w/elevated HR, Antihypertensive = Hypertension, 2nd line med for A-Fib/A-Flutter w/ RVR, & SVT
113
Rocuronium) Dynamics Indications: Contra: Dose:
= Nondepolarizing neuromuscular blocker. Binds to ACh receptors =DSI/RSI = Hypersensitivity = 0.6-1.2 mg/kg. TTP: 60-90 secs. DOP: 45-120 mins
114
Vecuronium) Dynamics: Indications: Contra: Dose:
= Nondepolarizing neuromuscular blocker. Binds to ACh receptors = DSI/RSI = Hypersensitivity = 0.1-0.2 mg/kg IV/IO. TTP: 1-3 mins. DOP: 45-90 mins.
115
Verapamil) class: pharmacodynamics:
= IV antiarrhythmic Ca channel blocker = Slows AP of autorhythmic cells in heart by blocking Ca channels
116
Verapamil) indications: Contraindications:
= 2nd med for A-Fib/Flutter w/ RVR, May use as alterative med (after adenosine), narrow QRS complex Tcardia w/ preserved LV function = HypoBP (SBP<90), CHF/cardio/ shock, Wide-complex Tcardia, WPW Hypersensitivity to med