Age-related macular degeneration Flashcards
1
Q
most common cause of blindness UK
A
macular degeneration
2
Q
key finding on fundoscopy in macular degeneration
A
drusen: yellow deposits of proteins & lipids between retinal pigment epithelium & Bruch’s membrane
3
Q
other signs found in AMD
A
- atrophy of retinal pigment epithelium
- degeneration of photoreceptors
4
Q
how do new vessels form in wet AMD, where do they form, what does that lead to
A
- VEGF
- choroid layer
- oedema
5
Q
RFs AMD
A
- age
- smoking
- white/chinese
- CVD
6
Q
classic presentation of macular degeneration
A
- gradual worsening CENTRAL visual field loss
- reduced visual acuity
- crooked/wavy appearance to straight lines
7
Q
which AMD is more acute
A
wet
8
Q
1st & 2nd line Ix wet AMD
A
- optical coherence tomography
- fluorescein angiography
9
Q
Mx dry degeneration
A
avoid RFs
10
Q
anti-VEGF meds used in Mx wet degeneration (injected in vitreous chamber) & how soon should they be started
A
- ranibizumab
- bevacizumab
- pegaptanib
- within 3 months
