Adrenaline

Question 1

MOA

Answer 1

Inotrope
Alpha 1 -blood vessels - vasoconstriction
Beta 1 - Heart - increase HR increase in inotropy (cardiac contractility),
Beta 2 - smooth muscle relaxation, skeletal muscle vasodilation, bronchodilation,

Question 2

Indications 7

Answer 2

cardiac arrest 
imminent respiratory arrest from CORD
anaphylaxis
severe asthma
severe bradycardia 
severe stridor
intranasal  -significant bleeding from the nose 
topical - significant bleeding from a wound.

Question 3

Contraindications

Answer 3

none

Question 4

Cautions 3

Answer 4

Myocardial ischaemia
Tachydysrhythmia
Use in pregnancy or when breastfeeding

Question 5

Dose and administration Route

Answer 5

Ampoule = 1mg in 1 ml

IM -
Draw up .05mg / .05 ml (1/2) into a 1 ml syringe. Attach 22g or 25g IM needle

Topical -Dilute each 1 ml of adrenaline to a total of 10 ml using 0.9% sodium chloride

Nebulised (Neb) five x 1mg/ml adrenaline ampoules and squirt into the nebuliser bowl. > Attach to nebuliser mask and set flow at 8l/m.

Intranasal -1 mg of adrenaline to a total of 10 ml using 0.9% sodium chloride -2 ml of this solution into each bleeding nostril