ADHD medications: stimulants and non stimulants Flashcards

1
Q

non stimulant adhd meds

A

atomoxetine
guanfacine
clonidine

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2
Q

3 sets stimulants for adhd

A

ampehtamine (d,l)
dextroamphetamine

lisdexamfetamine

methylpenidate (d,l)
dexmethylphenidate

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3
Q

stimulant moa

A

block presynaptic reuptake, interference with VMAT and increase NT release of SDN

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4
Q

methylphenidates main activity

A

inhibtion of DA reuptake and inhib of NT pre synaptic reuptake

doesn’t appear to stimulate release of NTs

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5
Q

lisdexamfetamine brand name

A

vyvanse

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6
Q

amphetamine brand names

A

adzenys, dyanavel, evekeo generic

ADE

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7
Q

dextroamphetamine brand names

A

dexedrine

procentra

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8
Q

methylpenidate brand names

A
ritalin
concerta
methylin (oral solution and ir chewable tab)
metadate
quillivant (oral suspension)
quillichew (chewable tab)
daytrana (patch)
aptensio XR
focalin XR
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9
Q

adzenys XR-ODT

A

amphetamine
50% IR 50% XR

A and Z meet in middle = 50/50

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10
Q

dyanavel formulation and class

A

XR liquid

amphetamine

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11
Q

dexederine spansules class, approved for what else

A

dextroamphetamines

narcolepsy

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12
Q

vyvanse generic and special

A

lisdexamfetamine, prodrug of dextroamphte

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13
Q

amphetamine salts

A

adderall xr (amphet/dextroamphet)
50/50 XR/IR
approved for narcolepsy

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14
Q

concerta generic and ir/xr and special delivery

A

methylphenidate
concerned about my meth head date
-instantly looks 22 so she loves OReOS

22 IR 78 ER

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15
Q

ritalin generic, release, delivery form

A

methylphenidate
tony murrill was on ritalin and loved SODAS
it was 50-50 that he was gay
LA 50% IR beads 50%

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16
Q

metadate CD, generic, release

A

methylphenidate
IR 30%/ CD 70%

control 70% of breathing when meditating

17
Q

aptensio XR generic, releaes

A

methylphenidate
IR= 40% XR= 60%

instantly kicked out of class if you are APTENSE for 40% of classes

18
Q

daytrana form, and generic

abuse potential?

A

patch
methylpenidate
low abuse potential

19
Q

quillichew ER generic and relsae

A

XR chewable d-methylpenidate

30% IR 70% XR
quick chew 30 pieces of gum

20
Q

quillivant XR generic and release

A

extended release oral d-methylpenidate

IR 20%, XR 80%
ill give you an XtRa 80 dollars to drink that quillvant

21
Q

focalin XR generic and release and special delivery

A

dexmethylphenidate

IR = 50 XR = 50
SODA

FOCA SODA half the time

22
Q

rare side effects of stimulants

A

seizures, priapism, sudden cardiac death (always assess for cardiac structural abnormalties)

stroke and MI

23
Q

possible AE with daytrana patch

A

chemical leukoderma

24
Q

caution using stimulants with pt with what? know rest, this seems odd

A

glaucoma

25
Q

main effect of non stimulatnt is to enhance NT transmiision via

A

inhibit NE reuptake (atomoxetine)

agonist of A2a adrenergic receptors: guanfacine and clonidine

26
Q

onset of activity for non stimulants

A

1-4 weeks

27
Q

strattera: generic and moa

A

atomoxetine
NET blocker

tom is high in the stratosphere bc tall and can block the NET

28
Q

AE of strattera or atomoxetine

A

all same as stimulants except no motor/vocal tics
no seixures

add suicidal ideations and severe liver injury/jaundice

think about tom. hes pale and jaundice and depressed, but he has no tics.

29
Q

caution using atomoxetine with people with

A

narrow angle glaucoma
mao inhibs
cyp2D6 inhibitors (think about tom being 26 and MAO for dep)

also don’t give to pts that have same conditions that you wouldnt give stimulants to

30
Q

downward dose titration over 1+ weeks for what drugs for ADHD and why

A

guanfacine and clonidine bc of rebound HTN

31
Q

side effects of a2 agonists

A

dyspepsia/GI distress
sedation/fatigue
hypotension/brandycardia, orthostatic hypotension

32
Q

rare side effects of a2 agonists

A

qtc prolong

AV block

33
Q

caution using a2 agonist with

A

CV disease

cardiac conduction abnormalities

34
Q

intuniv

A

guanfacine is intuniv

35
Q

kapvay

A

clonidine