ADHD medications: stimulants and non stimulants

Question 1

non stimulant adhd meds

Answer 1

atomoxetine
guanfacine
clonidine

Question 2

3 sets stimulants for adhd

Answer 2

ampehtamine (d,l)
dextroamphetamine

lisdexamfetamine

methylpenidate (d,l)
dexmethylphenidate

Question 3

stimulant moa

Answer 3

block presynaptic reuptake, interference with VMAT and increase NT release of SDN

Question 4

methylphenidates main activity

Answer 4

inhibtion of DA reuptake and inhib of NT pre synaptic reuptake

doesn’t appear to stimulate release of NTs

Question 5

lisdexamfetamine brand name

Answer 5

vyvanse

Question 6

amphetamine brand names

Answer 6

adzenys, dyanavel, evekeo generic

ADE

Question 7

dextroamphetamine brand names

Answer 7

dexedrine

procentra

Question 8

methylpenidate brand names

Answer 8

ritalin
concerta
methylin (oral solution and ir chewable tab)
metadate
quillivant (oral suspension)
quillichew (chewable tab)
daytrana (patch)
aptensio XR
focalin XR

Question 9

adzenys XR-ODT

Answer 9

amphetamine
50% IR 50% XR

A and Z meet in middle = 50/50

Question 10

dyanavel formulation and class

Answer 10

XR liquid

amphetamine

Question 11

dexederine spansules class, approved for what else

Answer 11

dextroamphetamines

narcolepsy

Question 12

vyvanse generic and special

Answer 12

lisdexamfetamine, prodrug of dextroamphte

Question 13

amphetamine salts

Answer 13

adderall xr (amphet/dextroamphet)
50/50 XR/IR
approved for narcolepsy

Question 14

concerta generic and ir/xr and special delivery

Answer 14

methylphenidate
concerned about my meth head date
-instantly looks 22 so she loves OReOS

22 IR 78 ER

Question 15

ritalin generic, release, delivery form

Answer 15

methylphenidate
tony murrill was on ritalin and loved SODAS
it was 50-50 that he was gay
LA 50% IR beads 50%

Question 16

metadate CD, generic, release

Answer 16

methylphenidate
IR 30%/ CD 70%

control 70% of breathing when meditating

Question 17

aptensio XR generic, releaes

Answer 17

methylphenidate
IR= 40% XR= 60%

instantly kicked out of class if you are APTENSE for 40% of classes

Question 18

daytrana form, and generic

abuse potential?

Answer 18

patch
methylpenidate
low abuse potential

Question 19

quillichew ER generic and relsae

Answer 19

XR chewable d-methylpenidate

30% IR 70% XR
quick chew 30 pieces of gum

Question 20

quillivant XR generic and release

Answer 20

extended release oral d-methylpenidate

IR 20%, XR 80%
ill give you an XtRa 80 dollars to drink that quillvant

Question 21

focalin XR generic and release and special delivery

Answer 21

dexmethylphenidate

IR = 50 XR = 50
SODA

FOCA SODA half the time

Question 22

rare side effects of stimulants

Answer 22

seizures, priapism, sudden cardiac death (always assess for cardiac structural abnormalties)

stroke and MI

Question 23

possible AE with daytrana patch

Answer 23

chemical leukoderma

Question 24

caution using stimulants with pt with what? know rest, this seems odd

Answer 24

glaucoma

Question 25

main effect of non stimulatnt is to enhance NT transmiision via

Answer 25

inhibit NE reuptake (atomoxetine) | agonist of A2a adrenergic receptors: guanfacine and clonidine

Question 26

onset of activity for non stimulants

Answer 26

1-4 weeks

Question 27

strattera: generic and moa

Answer 27

atomoxetine NET blocker tom is high in the stratosphere bc tall and can block the NET

Question 28

AE of strattera or atomoxetine

Answer 28

all same as stimulants except no motor/vocal tics no seixures add suicidal ideations and severe liver injury/jaundice think about tom. hes pale and jaundice and depressed, but he has no tics.

Question 29

caution using atomoxetine with people with

Answer 29

narrow angle glaucoma mao inhibs cyp2D6 inhibitors (think about tom being 26 and MAO for dep) also don't give to pts that have same conditions that you wouldnt give stimulants to

Question 30

downward dose titration over 1+ weeks for what drugs for ADHD and why

Answer 30

guanfacine and clonidine bc of rebound HTN

Question 31

side effects of a2 agonists

Answer 31

dyspepsia/GI distress sedation/fatigue hypotension/brandycardia, orthostatic hypotension

Question 32

rare side effects of a2 agonists

Answer 32

qtc prolong | AV block

Question 33

caution using a2 agonist with

Answer 33

CV disease | cardiac conduction abnormalities

Question 34

intuniv

Answer 34

guanfacine is intuniv

Question 35

kapvay

Answer 35

clonidine