Addiction: Reducing Addiction - Drug Therapy Flashcards
What is the drug therapy for nicotine addiction?
Nicotine replacement therapy
What is NRT?
A agonist substitution
What does NRT do?
Increases neurotransmitter activity
What is the aim of NRT?
Provide nicotine from a less harmful source
1 - How does NRT work?
Stimulates the nicotine receptors and activates the brain’s reward pathway
Releases dopamine into the limbic system
Stimulates the nucleus accumbens, creates pleasureable feeling
1 - What does NRT lead to?
A reduction in nicotine withdrawal symptoms
Stops cravings
1 - What is the withdrawal symptom an example of?
Negative reinforcements as the NRT removes the unpleasant circumstances of quitting smoking
2 - What does NRT also do?
Desensitises the nicotine receptors in the brain by releasing small amounts of nicotine so that ony some receptors are full with nicotine, not all
2 - Over time what happens to the nicotine receptors?
Reduce which means the cigarettes become less rewarding to smoke
Relapse is less likely
Gradually reduce the dosage of nicotine as thei tolerance to nicotine is reduced as the tolerance is reduced
What is the drug therapy for gambling addiction?
Opioid Antagonist
What does the opioid antagonist do?
Reduce neurotransmitter activity
What is the aim of opioid antagonist?
Reduce the pleasureable feeling associated with gambling
How does the opioid antagonist work?
Enhances the release of neurotransmittrers GABA in the mesolimbic pathway
What deos the increased GABA activity ?
Reduces the release of dopamine in the nucleus accumbens
Linked with reductions in gambling behaviour
1 - Who researched the effectiveness of NRT?
Stead et al
1 - What did they do?
Reviewed 150 high quality studies that compared use of NRT with a placebo
1 - What did they find?
All forms of NRT (Inhalers,gums, patches) were significantly more effectice in helping smokers quit than placebos and no treatment at all
1 - What is the link?
Supports drug therapy as a way of reducing addiction, found to be very effective
Supports how reducing addiction can be achieved through giving nicotine in a less harmful way
2 - What is a limitation?
Negative side effects
2 - What are the common side effects?
Sleep disruption, stomach problems, dizziness and headaches
2 - What is this unlike?
CBT
2 - What is the link?
Side effects may cause individual to stop taking drug
Relapse in symptoms, drug therapy is ineffective
3 - What is a strength of drug therapy?
Requires little motivation and committment
3 - What does the patient have to do?
Only wear a patch or chew gum to reduce their addiction