Adaptive immunity II

Question 1

Example of bacteria that can survive inside a macrophage

Answer 1

Mycobacterium tuberculosis

Question 2

What type of T cell activates infected macophages?

Answer 2

TH-1

Question 3

TH1 macrophage activation

Answer 3

Enchanced macrophage function against intracellular pathogen. Recognition of antigenic peptides presented by MHC c. II.

Question 4

What 2 signals does activation of macrophage by TH1 cells require

Answer 4

Priming singal and CD40L binding on macrophage surface

Question 5

What disease is a common cause of death in AIDS?

Answer 5

TB

Question 6

TH-2 cells respond to what type of infection?

Answer 6

Intestinal parastites.

Question 7

How do TH2 cells respond to intestinal parasites?

Answer 7

IL-13, epithelial cell repair and mucus.
IL-5, recruits and activates eosinophil.
Signals B cell to produce IgE.
IL3, IL9: drives mast cell rec.

Question 8

What type of allergies are TH2 cells in?

Answer 8

Type I