Acute Monoarthritis and Spondyloarthropathies Flashcards
WHat bacterial usually goes to a synovial joint?
Pseudomonas
What are the mechanisms of Joint infection?
Hematogenous Spead: -IV Drugs, Catheters, Immcomp Bite/Trauma Direct Inoculation Extension of Bony infection
What joint is most commonly infected?
Knee, Wrist, hip
How is Septic Arthritis Dx?
Fluid Aspirate: Gram stain, culture, Cell count (50-150k WBCs), Crystal analysis
Blood culture
Acute Phase Reactants
Imaging
What are the traits of Gonococcal infection of a joint?
Gonococcal Infection
- Purulent Monoarthritis
- Triad: Tenosynovitis, vesiculopustular skin lesions, polyarthralgia
What are Causes of Nongonococcal Joint infections?
Staph aureus, Strep Pneumo, G-, Bucellosis
What are Fungal causes of Non-Bacterial Septic Arthritis?
Sporotrichosis
Cryptococcus
Blastomycosis
Coccidiomycosis
What is the Tx of Septic Arthritis?
Repeated Drainage
Abtx
What is micro appearance of in gout?
Negative Birefringent needle-like crystals under Polarized light
At what point will Uric Acid Precipitate?
over 7 mg/dl
Get levels below 6 in order to mobilize crystals in joints
What meds are given for Gout?
Colchicine
NSAIDS: Naproxen, Indomethacin
What is the cause of Pseudogout?
Calcium Pyrophosphate Crystal Deposition disease
What is the Tx of Pseudogout?
Oligoarticular- Joint injection- steroids
Polyarticular- NSAIDS, Colchicine, Oral Steroids
What is Spondyloarthritis?
Inflammation of the axial joints, asymmetrical oligoarthritis, dactylitis, enesthopathy
What Labs are used to diagnose Spondylo-arthropathies?
***HLA-B 27
ESR
CRP