Acute Monoarthritis and Spondyloarthropathies Flashcards

1
Q

WHat bacterial usually goes to a synovial joint?

A

Pseudomonas

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2
Q

What are the mechanisms of Joint infection?

A
Hematogenous Spead:
-IV Drugs, Catheters, Immcomp
Bite/Trauma
Direct Inoculation
Extension of Bony infection
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3
Q

What joint is most commonly infected?

A

Knee, Wrist, hip

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4
Q

How is Septic Arthritis Dx?

A

Fluid Aspirate: Gram stain, culture, Cell count (50-150k WBCs), Crystal analysis
Blood culture
Acute Phase Reactants
Imaging

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5
Q

What are the traits of Gonococcal infection of a joint?

A

Gonococcal Infection

  • Purulent Monoarthritis
  • Triad: Tenosynovitis, vesiculopustular skin lesions, polyarthralgia
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6
Q

What are Causes of Nongonococcal Joint infections?

A

Staph aureus, Strep Pneumo, G-, Bucellosis

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7
Q

What are Fungal causes of Non-Bacterial Septic Arthritis?

A

Sporotrichosis
Cryptococcus
Blastomycosis
Coccidiomycosis

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8
Q

What is the Tx of Septic Arthritis?

A

Repeated Drainage

Abtx

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9
Q

What is micro appearance of in gout?

A

Negative Birefringent needle-like crystals under Polarized light

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10
Q

At what point will Uric Acid Precipitate?

A

over 7 mg/dl

Get levels below 6 in order to mobilize crystals in joints

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11
Q

What meds are given for Gout?

A

Colchicine

NSAIDS: Naproxen, Indomethacin

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12
Q

What is the cause of Pseudogout?

A

Calcium Pyrophosphate Crystal Deposition disease

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13
Q

What is the Tx of Pseudogout?

A

Oligoarticular- Joint injection- steroids

Polyarticular- NSAIDS, Colchicine, Oral Steroids

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14
Q

What is Spondyloarthritis?

A

Inflammation of the axial joints, asymmetrical oligoarthritis, dactylitis, enesthopathy

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15
Q

What Labs are used to diagnose Spondylo-arthropathies?

A

***HLA-B 27
ESR
CRP

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16
Q

What is the Non Pharm Tx of SpA?

A

Stop Smoking, Exercise, Education

17
Q

What is the Pharm Tx of SpA?

A
NSAIDS
Analgesics 
Biologics
Imm-Supp
Anti-TNF Agents
18
Q

What is the difference in distribution between SpA and Reactive Arthritis?

A

SpA: Starts at Sacrum and Ascends

Reactive Arthritis: Spotty distribution (unpredictable)

19
Q

What are causes of Reactive Arthritis?

A

Virus, IBS, GU disorders, Gonococcal Infection

Spondyloarthropathy, Post Strep Arthritis-Rheum Fever