Acute and Chronic Inflammation Flashcards

1
Q

Fxn of Prostaglandin

A

P. F . C. ( Pain , Fever , Clotting )

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2
Q

Fxn of Leukotrienes

A

C. V. I ( Chemotaxis , Vasoconstriction , Increase Permeability )

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3
Q

Phagocytosis

A

R. E. K. ( Recognition , Engulfment , Killing )

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4
Q

Evokes Synthethase

A

Serotonin

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5
Q

Other name for Serotonin

A

5-Hydroxy-Tryptamine

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6
Q

Kinin 3 Actions

A

I. S . P. ( Increase permeability , Smoothmuscle contraction, Pain)

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7
Q

3 Free Radicals

A

O2 , H2O2 , OH-

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8
Q

Extravasion of PMNs

A

M.R.A.T. ( Margination , Rolling , Adhesion , Transmigration

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9
Q

Historical Highlights

A

R.C.T.D.F ( Rubor , Calor , Tumor , Dolor , Function Laesa)

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10
Q

3 Outcome of Acute inflammation

A

100% complete resolution
Scar
Chronic Inflammation

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11
Q

Neurpopeptides

A

Substance P , Neurokinin A

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12
Q

Morphologic Patterns of Acute Inflammation ( Exudate )

A

S F U S ( Serous , Fibrinous , Ulcerative , Suppurative )

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13
Q

Causes of Chronic Inflammation

A

Persistence of Infection
Prolonged Exposure to insult
Auto-immunity

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14
Q

Cellular Players

A

Lymphocytes , Macrophages , Plasma Cell , Eosinophil , Basophil

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15
Q

Increase Permeability

A
D . E .D . L. T. N.
Dilations
Endothelial Gap
Direct Injury
Leukocyte Injury
Transocytosis
New Vessels
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16
Q

Primary lysosomal contents

A

M.L.A.
Myeloperoxidase
Lysozyme
Acid Hydrolase

17
Q

Secondary lysosomal contents

A
L.L.A.C
Lactoferrin
Lysozyme
Alkaline phosphatase
Collagenase
18
Q

Atrophy

A

Decrease Workload , Blood Flow , Nutrition
Denervation
Aging
Pressure

19
Q

Necrosis Brother

A

L G F C F I A

20
Q

Normal Apoptosis

A
EHC-PEC
Embryogenesis
Hormonal-Involution
Cell population control
Post inflammatory Clean up
Elimination of Harmful cells
Cytotoxic Tcells cleaning
21
Q

Pathologic Apoptosis

A
T D T A
Toxic effects on cells
Duct Obstruction
Tumor Cells
Apoptosis/Necrosis Spectrum
22
Q

Apoptosis Biochemistry

A

Protein Digestion
DNA breakdown
Phagocytic Recognition