Acute and Chronic Inflammation Flashcards
Fxn of Prostaglandin
P. F . C. ( Pain , Fever , Clotting )
Fxn of Leukotrienes
C. V. I ( Chemotaxis , Vasoconstriction , Increase Permeability )
Phagocytosis
R. E. K. ( Recognition , Engulfment , Killing )
Evokes Synthethase
Serotonin
Other name for Serotonin
5-Hydroxy-Tryptamine
Kinin 3 Actions
I. S . P. ( Increase permeability , Smoothmuscle contraction, Pain)
3 Free Radicals
O2 , H2O2 , OH-
Extravasion of PMNs
M.R.A.T. ( Margination , Rolling , Adhesion , Transmigration
Historical Highlights
R.C.T.D.F ( Rubor , Calor , Tumor , Dolor , Function Laesa)
3 Outcome of Acute inflammation
100% complete resolution
Scar
Chronic Inflammation
Neurpopeptides
Substance P , Neurokinin A
Morphologic Patterns of Acute Inflammation ( Exudate )
S F U S ( Serous , Fibrinous , Ulcerative , Suppurative )
Causes of Chronic Inflammation
Persistence of Infection
Prolonged Exposure to insult
Auto-immunity
Cellular Players
Lymphocytes , Macrophages , Plasma Cell , Eosinophil , Basophil
Increase Permeability
D . E .D . L. T. N. Dilations Endothelial Gap Direct Injury Leukocyte Injury Transocytosis New Vessels