active transport Flashcards
define active transport
the movement of molecules and ions through a cell membrane from a region of lower concentration to a region of higher concentration using energy from respiration (ATP)
what proteins does active transport require?
carrier proteins
what provides the energy for active transport?
ATP
explain how active transport works with a carrier protein
- transport is through carrier proteins spanning the membrane
- molecule binds to a receptor complementary in shape on the protein
- ATP binds to the protein from the inside of the cell and is hydrolysed into ADP and Pi
- this causes the carrier protein to change shape and release the molecule to the other side
- the phosphate ion is then released and protein returns to its original shape
what is active transport important in?
- reabsorption of useful molecules and ions into the blood after filtration into the kidney tubules
- absorption of some products of digestion
- loading sugar from the photosynthesising of cells in leaves into phloem for transport
- loading inorganic ions from coil into root hairs
what is co-transport?
the coupled movement of substances across a cell membrane via a carrier protein. It involves both facilitated diffusion and active transport
explain the co-transport of sodium ions and glucose in the ileum
- sodium ions are actively transported out of the epithelial cells into the blood by the S-P pump. This creates a conc gradient - there’s a higher conc of Na ions in the lumen of the ileum than the epi cell. K is pumped in. requires ATP
- this causes sodium ions to diffuse into the epi cell from the lumen down their conc gradient. They do this via the S-G co-trans proteins. this carries glucose into the cell against its conc grad with Na, ‘’’ glucose conc in cell increases
- glucose diffuses out of the cell into the blood own its conc gradient through a protein channel by facilitated diffusion. The blood carries it away which maintains the low conc
what factors affect the rate of active transport?
- the speed of individual carrier proteins- if they’re faster, the rate will be faster
- the number of carrier proteins- more proteins means faster rate
- the rate of respiration in the cell and the availability of ATP. If respiration is inhibited, active transport can’t take place
what increases the surface area on epithelial cells for co-transporter proteins?
microvilli
what is the ultimate aim of co-transport in the small intestine?
to get glucose into the bloodstream
Name and describe five ways substances can move across the cell-surface membrane into a cell
- diffusion of small/non-polar molecules down a concentration gradient
- Facilitated diffusion down a concentration gradient via protein carrier/channel
- Osmosis of water down a water potential gradient
- Active transport against a concentration gradient via protein carrier using ATP
- Co-transport of 2 different substances using a carrier protein
Explain the function of ATP hydrolase in co transport
(ATP to ADP + Pi ) Releases energy
(energy) allows ions to be moved against a concentration gradient/allows active transport of ions
The movement of Na+ out of the cell allows the absorption of glucose into the cell lining the ileum. Explain how.
(Maintains/generates) a concentration/diffusion gradient for Na+ (from ileum into cell);
Na+ moving (in) by co-transport, brings glucose with it
Describe and explain two features you would expect to find in a cell specialised for absorption
larger number of mitochondria for ATP
larger number of carrier proteins/co transporters
microvilli for large surface area