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CC 2 LEC FINALS > ACTH- ONG > Flashcards

ACTH- ONG Flashcards

1
Q

Secreted when the cortisol level is low

A

ACTH

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2
Q

Regulator of adrenal androgen synthesis

A

ACTH

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3
Q

cell will stop growing; eventually it will decrease in size and tissue will disappear

A

Atrophy

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4
Q

Atrophy in the____

A

Zona Glomerulosa & Reticularis

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5
Q

Tumors formed because of the proliferation of the cells.

A

Ectopic tumors

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6
Q

ACTH SAMPLE CONTAINER

A

Pre-chilled EDTA tubes

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7
Q

ACTH has a tendency to adhere to the glass tubes
Leads to_____ ACTH level

A

falsely-decreased

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8
Q

Structurally related to lactogen and GH

A

PROLACTIN (PRL)

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9
Q

🗣️Beside PRL what hormone is considered lactogenic?

A

✔ Oxytocin

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10
Q

Also known as “Stress hormone” or direct effector hormone

A

PROLACTIN

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11
Q

Most UNIQUE among the anterior pituitary hormone which is regulated through tonic inhibition

A

PROLACTIN

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12
Q

Even with the presence of stimuli, it will respond late but has a long-lasting inhibition

A

TONIC INHIBITION

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13
Q

Rapid response to stimuli but short-term

A

PHASIC INHIBITION

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14
Q

🗣️How is the neurohypophysis connect with hypothalamus?

A

✔ Hypophyseal Portal System

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15
Q

cells producing PRL

A

Lactotrophs

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16
Q

Can reach up to 150 ng/mL PRL secretion

A

Result to anovulation

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17
Q

For men, if they have excessive production of PRL it can result to:

A

Reduced libido & erectile dysfunction

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18
Q

But if greater than 150, that is considered as _____

A

prolactinoma.

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19
Q

🗣️Why is TSH & fT4 necessary?

A

✔ To help eliminate primary hypothyroidism as the cause of elevation of PRL

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20
Q

If value of PRL is greater than 200, it is due ___

A

to the problem in the adenohypophysis or hypothalamus

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21
Q

Pan means _____

A

“all “ or “complete”

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22
Q

Abnormal levels of TSH and fT4 indicates____

A

Primary Hypothyroidism

23
Q

Complete loss of function of the adenohypophysis

A

Primary Hypothyroidism

24
Q

Oma: tumors =

A

adenoma & craniopharyngioma

25
Q

local anemia (1 portion of the body is anemic); decreased blood supply to an organ or tissue

A

Ischemia:

26
Q

Result of blood loss or hemorrhage or shock in a pregnant woman also known as _____

A

Postpartum Pituitary gland Necrosis

27
Q

_____ does NOT directly secrete hormones but rather holds or stores hormones coming from the hypothalamus specifically Vasopressin and Oxytocin

A

Neurohypophysis

28
Q

Supraoptic nuclei:

A

Vasopressin

29
Q

Paraventricular nuclei:

A

Oxytocin

30
Q

____ is released by neurohypophysis in response to suckling of the baby or in anticipation for delivery

A

Oxytocin

31
Q

____means uterus of a woman ready for the delivery of a child;in the last trimester

A

Gravid uterus

32
Q

Receptors are found on the ____ in the uterus or ____ in the breast

A

myometrial cell membrane,myoepithelial cell membranes

33
Q

____: days of labor but baby is NOT there yet, NO contraction

A

Synthetic Preparations

34
Q

Hormone produced in the hypothalamus and stored in the posterior pituitary gland

A

AVP

34
Q

Hormone produced in the hypothalamus and stored in the posterior pituitary gland

A

AVP

35
Q

TARGET ORGAN OF AVP

A

Distal convoluted and collecting tubules

36
Q

AVP : URINE PRODUCTION

A

DECREASE

37
Q

AVP: BP

A

INCREASED

38
Q

What secretes the AVP?

A

✔ Hypothalamus

39
Q

🗣️What is the effect once there is a signal received by the neurohypophysis? What will happen?

A

In the case of AVP, it can stimulate the aquaporins to open

40
Q

After the hormone receptor complex couples with ____, there is cleavage of PIP2 (Phosphatidylinositol 4,5-bisphosphate) which causes the production of IP3 (Inositol Triphosphate) and DAG (Diglycerol)

A

phospholipase C

41
Q

3Ps: ____

A

Polyuria, Polydipsia, Polyphagia

42
Q

DIFFERENCES OF DM AND DI

A

Diabetes Mellitus: increase level of glucose in the blood along with the 3Ps
Diabetes Insipidus: 3Ps with normal glucose level

43
Q

Excessive urine production

A

(greater than 2,000mL/20L per day

44
Q

🗣️Why is there excessive thirst?

A

If the patient has DI and hypothalamic thirst center is intact.

45
Q

Normal ADH, impaired ADH receptors

A

NEPHROGENIC DI

46
Q

Kidneys fail to respond to ADH levels

A

NEPHROGENIC DI

47
Q

ADH deficient, normal ADH receptor

A

NEUROGENIC DI

48
Q

OVERNIGHT WATER DEPRIVATION TEST OTHER NAME

A

Concentration Test

49
Q

Serum/ Plasma osmolality is measured every

A

4 hrs

50
Q

Urine volume/osmolality is measured every

A

2 hrs

51
Q

🔊After administration of desmopressin, if urine osmolality still remains below 300 mOsm/kg even a

A

NEPHROGENIC DI

52
Q

After administration of desmopressin, if urine osmolality remains below 300 mOsm/kg and rises greater than 800 after desmopressin

A

NEUROGENIC DI

CC 2 LEC FINALS (8 decks)

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