acronyms Flashcards

1
Q

which protein synthesis inhibitors attack which ribosomal subunits

A

Buy AT 30 CCELL at 50

30s subunit:
Aminoglycosides
Tetracyclines

Chloramphenical
Clindamycin
Erythromycin
Linezolid
Lincomycin
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2
Q

what are the therapeutic uses of tetracyclines like tetracycline, doxycycline, and minocycline

A

VACUM THe BedRoom

Vibrio Cholerae
Achne
Chlamydia
Ureaplasma urealyticum
Mycoplasma pneumoniae
Tularemia
Helicobacter pylori
Borrelia burgdoferi
Rickettsia
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3
Q

drugs causing phototoxicity

A

SAT for a photo

Sulfonamides
Amioderone
Tetracycline

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4
Q

how do these three antibiotics work

Aminoglycosides
Tetracyclines
Macrolides

A

Aminoglycosides:
A “initiates” the alphabet–>aminoglycosides inhibit formation of initiation complex

Tetracyclines:
prevent attachment of ammoniacal-Trna

Macrolides:
macroSLIDES–>inhibit protein synthesis by blocking translocation

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5
Q

what does macrolides treat

A

PUS

Pneumonia-atypical (mycoplasma, chlamydophilia, legionella)
URI (S. pneumoniae, S. pyogenes)
STD (chlamydia, Gonorrhea)

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6
Q

what is the pneumonic to remember drugs you wouldn’t think are self drugs

A

Sulfa Pills Frequently Cause Terrible Acute Symptoms

Sulfasalazine
Probenacid
Furosemide
Celecoxib
Thiazides
Acetazolamide
Sulfonylureas
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7
Q

what are the clinical uses of Metronidazole

A

GET GAP on the METRO

Protozoa:
Giardia
Entomeaba Histolytica
Trichomonas

Bacteria:
Gardnerella vagininalis
Anaerobic bacteria
Pylori (H. pylori)

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8
Q

what are the signs and symptoms of Lesch-Nyhan syndrome

A

defect in HGPRT enzyme for purine salvage pathway

Hyperuricemia
Gout
Pissed off (aggression, lip biting)
Retardation
dysTonia
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9
Q

what do the eukaryote polymerases alpha, beta, delta, and gamma each do respectively

A

Alpha
synthesize the lAgging strand

Delta
synthesize the leaDing strand

Beta
Base excision repair

gamma is your GRANDMAs polymerase
synthesize Mitochondrial DNA

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10
Q

what is the start codon

what is the stop codons

A

AUG inAUGurates protein synthesis (codes for methionine)

UGA=U Go Away
UAA= U Are Away
UAG= U Are Gone

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11
Q

what are the Rs of rifampin

A

it inhibits prokaryote Rna polymerase
Red secretions
RRRRRRevs up cytochrome p450

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12
Q

what end of the tRNA does aminoacyl-tRNA synthetase add an amino acid

A

3’ at CCA (Can Carry Amino acids)

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13
Q

what are two syndromes demonstrate imprinting (at a loci one allele is active and the other is inactive depending on inheritance)

A

Prader-will syndrome and angelman syndrome

MAMA and POP diseases

Maternal gene
Angelmans
Mood-innapropriate happiness and laughter
Ataxia

Prader-Wili
Overeating, obesity
Paternal gene

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14
Q

what are the low potency antipsychotics which have a lot of anticholinergic, hypotension, and histamine side effects

A

Chlo and Thio are LOW thieves

Chlorpromazine
Thioridazine

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15
Q

What are the high potency antipsychotics which have less anticholinergic side effects but instead have extra pyramidal symptoms, neuroleptic malignant syndrome, and tardive dyskinesia

A

Tri to Fly HIGH

Trifluoperazine
Fluphenazine
Haloperidol

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16
Q

what are the atypical antipsychotics which have fewer extrapyrimidal and anticholinergic side effects but may cause weight gain

A

A! Ola, could you get cloz and risper quet

Apiprazole
Olanzapine
Clozapine
Risperidone
Quetiapine
17
Q

what are the sign and symptoms a patient needs at least three of for him her to be considered to be having a manic episode

A

DIG FAST

Distractibility
irresponsibility
Grandiosity

Fast thoughts and speech
Activities/Agitation (does a million goals in a short amount of time)
decreased need for Sleep
Time (needs to be at least a weeks)

18
Q

what are the side effects of lithium

A

LMNOP

Lithium side effects
Movement (tremor)
Nephrogenic diabetes insipidus
HypOthyroidism
Pregnancy problems
19
Q

to diagnose major depressive disorder a patient must have at least 5 symptoms of 2 or more weeks. what are these symptoms

A

Must have depressed mode or anhedonia

then SIG E CAPS

Sleep disturbances
lost of Interest
Guilt or feelings of worthlessness
Energy loss (fatigue)
Concentration problems
Appetite/weight changes
Psychomotor retardation or agitation
Suicidal ideations (or just an interest in death)
20
Q

what are the symptoms of overdose by TCAs

A

the Tri-Cs

CNS toxicity –coma, convulsions
anitCholnergic effect
Cardiotoxicity