acid base imbalances Flashcards

1
Q

acid

A

electrolyte with ions in water to form hydrogen ions and anions

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2
Q

base

A

a substance that can bind to hydrogen ions

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3
Q

normal blood pH

A

7.35-7.45

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4
Q

What blood pH does death occur

A

less than 6.8
over 7.8

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5
Q

volatile acids

A

can be exerted from the body as a gas

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6
Q

Nonvolatile acids

A

Must be excreted via kidneys as liquid
Lactic acid, ketones, phosphoric acid, sulfuric acid
Typical american diet causes overload

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7
Q

Excretion of acids

A

Lungs excrete volatile (CO2)
Kidney excrete nonvolatile and retain bicarb as a buffer for acids (eliminate H+ and generate HCO3-)

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8
Q

CO2 and HCO3- acid or base

A

CO2 acid
HCO3- base

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9
Q

High CO2

A

Hypercapnia
increased ventilation

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10
Q

Low CO2

A

Hypocapnia
decreases ventilation

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11
Q

What do kidneys excrete and retain

A

Excrete H+ ions attached to NH4 (ammonia)
Retain sodium bicarb (most common buffer

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12
Q

Lab findings of respiratory acidosis

A

pH below 7.35
CO2> 45mm Hg
HCO3 normal
Urine pH below 6

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13
Q

Manifestations of resp acidosis

A

Neuro drowsy, disoriented, coma
Cardio hypotension, tachy
respiratory shallow, tachy/brady
Muscular: weakness

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14
Q

Causes of respiratory alkalosis

A

Hyperventilation (anxiety, encephalitis, fever, mechanical overventilation)

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15
Q

La values for respiratory alkadosis

A

pH >7.45
CO2 <35mmHg
HCO3 normal
Urine pH >7

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16
Q

Manifestations of respiratory alkalosis

A

Lethargic
confused
numbness
tingling
Muscular: tetany, hyperreflexia
Respiratory: hyperventilation

17
Q

causes of metabolic acidosis

A

Excess production of acids (diabetic ketoacidosis, lactic aciosis, starvation with lactic acidosis)
Inadequate loss of acids (uremia, renal tubular acidosis)
Excessive loss of base (severe diarrhea)

18
Q

Lab findings in metabolic acidosis

A

pH <7.35
CO2 normal
HCO2 <24
Urine pH <6

19
Q

Manifestations of metabolic acidosis neuro GI resp

A

Neuro: disoriented, weak, coma
GI: nausea, vomiting, diarrhea, abdominal pain, dehydration
Resp: hyperventilation

20
Q

causes of metabolic alkalosis

A

Loss of acids (severe vomiting, excess gastric suctioning, diuretic therapy)
Base or buffer imbalance (K+ deficit causing Na+ excess)
Excessive bicarb intake

21
Q

Lab findings of metabolic alkadosis

A

pH>7.45
CO2 normal
HCO3 >24
Urine pH >7

22
Q

Normal values (Co2, pH, HCO3, Hgb, CO)

A

CO2 38-43
pH 7.35-7.45
HCO3 22-26
Hgb 13-15
CO 0