Acid/Base Balance Flashcards
4 components of blood gas of interest:
PaO2
PaCO2
pHa
HCO3
Acidotic pH
Alkalotic pH
<7.35
>7.45
Normal 7.40
HCO3 and pH relationship
Direct correlation.
What mechanisms can affect pHa? (4)
Kidneys, which regulate HCO3 levels.
GI secretions of HCO3 or H+. Can be lost with vomiting/diarrhea.
Ingestion of antacids.
Metabolic problems (too much, lactic acid, ketoacids, etc.)
Changes in bicarbonate (HCO3) cause:
Metabolic disturbances
Gas equation
CO2 + H20 –> H2CO3 –> H+ + HCO3
CO2 and pHa relationship
Inverse correlation.
Changes in CO2 cause:
Respiratory disturbances
Metabolic acidosis is:
Decrease in HCO3, causing a decrease in pHa.
Metabolic alkalosis is:
Increase in HCO3, causing an increase in pHa.
Respiratory acidosis is:
Increase in CO2 , causing a decrease in pH.
Respiratory alkalosis is:
Decrease in CO2, causing an increase in pH.