Acetylcholine Flashcards
1
Q
Synthesis
A
Acetylcholine is formed from choline within neurons. The enzyme choline acetlytransferase transfers an acetyl group from acetyl coenzyme-A to choline resulting in acetylcholine.
2
Q
Breakdown
A
Acetylcholine is inactivated and broken down to choline and acetate by acetylcholinesterase.
3
Q
Receptors
A
The two main types of acetylcholine receptor are:-
Nicotinic
Muscarinic
Nicotinic receptors are ionotropic and are stimulated by nicotine and acetylcholine.
Muscarinic receptors are metabotropic and are stimulated by muscarine and acetylcholine.