Abx overview Flashcards
What are the 5 mechanisms of action seen with Abx?
1) Bacterial wall synthesis
2) Protein synthesis
3) DNA synthesis
4) Folic acid synthesis
5) Bacterial protein synthesis
What Abx are associated with bacterial wall synthesis?
Penicillins
Cephalosporins
Carbapenems
Vancomycin
What Abx are associated with protein synthesis?
Aminoglycosides
Macrolides
Tetracyclines
Metronidazole
What Abx are associated with DNA synthesis?
Fluoroquinolones
What Abx are associated with folic acid synthesis?
Sulfonamides
What Abx are associated with bacterial protein synthesis?
Clindamycin
What Abx is in the glycopeptide drug class?
Vancomycin
What Abx is in the lincosamide drug class?
Clindamycin
What Abx is in the nitroimidazole drug class?
Metronidazole
List the broad spectrum Abx? Hint: 9
Fluoroquinolones
Macrolides
Clindamycin
Tetracycline
Penicillins (amoxicillin, ampicillin, & piperacillin)
Cephalosporins
Aminoglycosides
Sulfonamides
Carbapenems
List the narrow spectrum Abx? Hint: 3
Vancomycin
Metronidazole
Penicillins (PCN G & PCN V)
List the Abx effective against gram (-) bacteria ONLY:
Aminoglycosides
What Abx can treat both gram (+) & gram (-) but are MORE effective against gram (-)?
Fluoroquinolones
3rd generation Cephalosporins
List the Abx effective against BOTH gram (+) & gram (-) bacteria: Hint: 6
Penicillins
1st-5th gen Cephalosporins
Fluoroquinolones (mainly (-))
Sulfonamides
Tetracyclines
Carbapenems
List the Abx effective against gram (+) bacteria ONLY:
Macrolides
Clindamycin
Vancomycin
Which Abx treats both gram (+) & gram (-) bacteria but MORE effective against gram (+)?
1st gen Cephalosporins
GI infections & UTIs are more commonly associated with what gram stain?
Gram (-) bacteria
List the gram-negative bacterias: Hint: 7
1) E. coli
2) Acinetobacter
3) Klebsiella
4) Pseudomonas Aeruginosa
5) Haemophilus Pneumoniae
6) Neisseria Meningitidis
7) Proteus Miralis
List the gram-positive bacterias: Hint: 12
1) Staphylococcus Aureus (including MRSA)
2) Streptococcus/ Streptococcus Pneumoniae
3) Legionella
4) Lyme’s Disease
5) Endocarditis
6) Sinusitis
7) STIs
8) Anaerobic bacterias
9) Mycobacteriums
10) Listeria
11) Bacterial vaginosis
12) Group A Beta Hemolytic Strep
List the beta-lactam Abx:
Hint: Pretty Cool Cars
Penicillins
Cephalosporins
Carbapenems
List the Bacteriostatic Abx:
Hint: Mighty Lions Slay Tigers
1) Macrolides
2) Lincosamides (Clindamycin)
3) Sulfonamides
4) Tetracyclines
List the Bactericidal Abx:
Hint: Powerful Cats Attack Fast Gazelles
1) Penicillins
2) Carbapenems
3) Aminoglycosides
4) Fluoroquinolones
5) Glycopeptides (Vancomycin)
List the Abx that is considered BOTH Bactericidal & Bacteriostatic?
Cephalosporins
