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Abx contraindications/ adverse effects Flashcards

1
Q

What Abx are contraindicated in those with known allergies to the drug?

A

Penicillins
Aminoglycosides
Cephalosporins
Carbapenems
Sulfonamides
Tetracyclines

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2
Q

What Abx are contraindicated in those with renal impairment/ disease?

A

Aminoglycosides
Cephalosporins
Carbapenems

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3
Q

What Abx should be used with caution in those with renal impairment?

A

Penicillins
Sulfonamides

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4
Q

What Abx are contraindicated in those with hepatic impairment/ disease?

A

Aminoglycosides
Cephalosporins

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5
Q

What Abx should be used with caution in those with hepatic impairment?

A

Macrolides
Metronidazole

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6
Q

What Abx is contraindicated in those with pre-existing hearing loss?

A

Aminoglycosides

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7
Q

What Abx is contraindicated in those with active herpes?

A

Aminoglycosides

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8
Q

What Abx is contraindicated in those with active mycobacterium infection?

A

Aminoglycoside

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9
Q

What Abx are contraindicated in those with myasthenia gravis?

A

Aminoglycosides
Fluoroquinolones

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10
Q

What Abx is contraindicated in those with Parkinson’s?

A

Aminoglycosides

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11
Q

What Abx are contraindicated in pregnant women?

A

Cephalosporins
Fluoroquinolones
Sulfonamides
Tetracyclines
Vancomycin

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12
Q

What Abx are contraindicated in those who are lactating?

A

Aminoglycosides
Cephalosporins
Carbapenems
Fluoroquinolones
Tetracyclines
Vancomycin

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13
Q

What Abx is contraindicated in those with seizure disorders?

A

Carbapenems

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14
Q

What Abx is contraindicated in those Dx with Meningitis?

A

Carbapenems

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15
Q

What Abx are contraindicated in children under 18 yrs old?

A

Fluoroquinolones
Sulfonamides

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16
Q

What Abx are contraindicated in children under 8 yrs old?

A

Tetracyclines

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17
Q

What Abx cause GI adverse effects? Hint: 10

A

Penicillins
Aminoglycosides
Cephalosporins
Carbapenems
Fluoroquinolones
Macrolides
Sulfonamides
Tetracyclines
Vancomycin
Metronidazole

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18
Q

What Abx can cause superinfections? Hint: 5

A

Penicillins
Cephalosporins
Carbapenems
Macrolides
Tetracyclines

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19
Q

What Abx can cause pain at the injection site?

A

Penicillins

20
Q

What are common Abx we see hypersensitivity associated with? (3)

A

Penicillins
Macrolides
Tetracyclines

21
Q

What Abx can cause CNS effects? (6)

A

Aminoglycosides
Cephalosporins
Carbapenems
Fluoroquinolones (black box)
Macrolides
Sulfonamides

22
Q

What Abx can cause nephrotoxicity?

A

Aminoglycosides
Cephalosporins
Vancomycin

23
Q

What Abx can cause ototoxicity?

A

Aminoglycosides
Vancomycin

24
Q

What Abx can cause cardiotoxicity?

A

Aminoglycosides

25
What Abx has a black box warning for tendonitis & Achilles tendon rupture?
Fluoroquinolones
26
What Abx has a black box warning for peripheral neuropathy & possible risk of AAA?
Fluoroquinolones
27
What Abx can cause QT prolongation?
Fluoroquinolones Macrolides
28
What Abx can cause hypoglycemia?
Fluoroquinolones Sulfonamides
29
What Abx can cause photosensitivity?
Fluoroquinolones Sulfonamides
30
What Abx can cause immunologic effects?
Fluoroquinolones
31
What Abx can cause renal issues; & what labs do you monitor?
Sulfonamides BUN/ Cr
32
What Abx can cause bone marrow depression?
Sulfonamides
33
What Abx can cause rashes/ itching?
Sulfonamides
34
What Abx can cause Steven-Johnson's Syndrome?
Sulfonamides Metronidazole
35
What Abx can cause hepatotoxicity?
Tetracyclines
36
What Abx can cause skeletal issues affecting: bone growth & mineralization?
Tetracyclines
37
What Abx can cause local effects?
Tetracyclines
38
What Abx can cause effects to the skin?
Tetracyclines Sulfonamides
39
What Abx can cause hematologic Sx?
Tetracyclines
40
What Abx can cause fatal pseudomembranous colitis?
Clindamycin
41
What Abx can increase risk of C. diff?
Cephalosporins Carbapenems Macrolides Clindamycin
42
What Abx can cause phlebitis at IV site?
Cephalosporins Vancomycin
43
What Abx can cause headaches?
Metronidazole
44
What Abx can cause xerostomia (dry mouth)?
Metronidazole
45
What Abx can cause Disulfiram-like reactions? And what should patients avoid to prevent this?
Metronidazole (Patients should avoid alcohol intake)
46
What Abx can cause abscesses at IM site?
Cephalosporins

NUR516 (36 decks)

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