ABx Flashcards
3 strains of bacteria causing menigitis
Pneumococcus
H flu
meningococcus
Intra-abdominal cluster bacteria
Gram negative aerobic bacilli
Anaerobes
Enterococus
what are the bacteriostatic drugs?
Macrolides tetracyclines Nitrofurantoin can be both static and cidal Clindamycin Linezolid
Amoxicillin with Clavulanate covers
Broad spectrum
gram positive aerobic cocci
gram negative aerobic cocci and bacilli
Most anaerobes
Piperacillin - covers especially which bacteria
Broad spectrum - broad gram negative coverage
AND PSEUDOMONAS
Cloxacillin covers importantly
Staph Aureus - mostly gram positive!
Cephalosporins dont cover which bug?
Enterococcus
First generation Ceph
CeFAzolin
CeFAlexin
Second generation Cephs
CefurOXime
CefOXitin
Third gen Cephs
CefTRIAxone
CefTAZidime
CefIXime
Fourth gen Ceph
Cefepime
Ciprofloxacin for which bacteria?
Gram negative aerobic bacilli - particularly Pseudomonas
some gram positive
Resp fluoroquinolones - what do they cover?
- Levofloxacin
- Moxifloxacin
- Ofloxacin
Gram neg aerobic bacilli (less Pseudomonas coverage) Pneumonia causing bacteria Aerobic gram positive cocci NOT Enterococcus Mox - covers most anaerobes
What are the pneumonia causing bacteria
S. pneumo H flu Mycoplasma C. Pneumoniae Legionella
Macrolides normally covers
E, A, C!
EAC - Gram positive cocci - NOT enterococus
AC - Bacteria which cause pneumonia
C- some gram negatives - travelers diarrhea, and gonorrhea
Tetracyclines - dox
Bacteria which cause pneumonia
Chlamydia
Atypical stuff!!
broad spectrum - YES MRSA -esp. Tigecycline
MRSA will need what Abx ?
- Tigecycline - tetracycline
- Septra?
- Clindamycin
- Vancomycin, Linezolid
Bacteria causing pneumonia - which Abx should be used?
- Macrolide
- Resp FQs
- Tetracycline
Aminoglycosides used when?
Aerobic gram negative bacilli
Carbapenems -
Fairly broad!!
not good for MRSA and enterococus
Trimethoprim - Sulfamethoxazole/Septra/Bactrim
Broad -
esp imp for UTIs
Pneumocystis Jirovecci as well
MRSA!
Nitrofurantoin covers
Gram negative aerobic bacilli - only used for cystisis
Enterococcus - only in urine
Metronidazole/Flagyl
C diff
Anaerobes!
Clindamycin
Aerobic Gram positive cocci , some Anerobes
MRSA!
NOT Enterococcus
Anaerobes above the diaphragm
Vancomycin, Linezolid
Always available for gram positives!!
Aerobic Gram positive cocci
Include Enterococcus and MRSA
vancomycin PO covers C. diff
Which 2 families of Abx used for out patients? for sick patients?
- Macrolides/ Tetracyclines
2. Aminoglycosides/carbapenems
Group A strep infection - Abx
1st choice: Penicillin/ Amox
2nd choice: 1st gen Ceph
- Macrolide
- Resp FQ
Vanco
Clind
Strep Pneumo or pneumococcus - Abx to use
1st choice: Pen/Amox
2nd choice: 2nd or 3rd gen ceph
- Macrolide
- Resp FQ!!!!
Dox
Vanco
Enterococcus Abx to use
- Amox/Amp
2. Vancomycin/Linezolid
Staph. Aureus
- If methicilin sensitive –> Cloxacillin
2. 1st gen ceph or vanco
MRSA Abx
Bloodstream 1. Vanco 2. Linezolid
Skin/soft tisse 1. Clindamycin 2. Septra/Dox
If you had a gram negative bacteria - what are the first choice Abx ?
If outpatient
- think of FQs –> CIPROFLOXACIN
- Cephalosporins
- Broad spectrum Penicilin - Amox-Clav
If you had a gram negative bacteria - what are the first choice Abx ?
If inpatient
- Aminoglycoside
- Piptazo
- Carbapenems
If you had a respiratory tract Gram negative? H. Flu, Moraxella Catarrhalis
- Amox - Clav
- Ceph - 2nd or 3rd gen
- Resp FQs
- Macrolide - C A!
If you had legionella (Gram neg)
Macrolide
Resp FQs
N. Meningitidis
N. Gonorrhea
3rd gen ceph (esp. Ceftriaxone)
Azithromycin or Doxycycline fo gonorrhea
chlamydia trachomatis
Chlamydia pneumoniae
Mycoplasma pneumoniae
- Azithromycin
- Dox
FQ
- Ofloxacin for C. trachomatic
- RFQ for pneumoniae
Anaerobes!
Metronidazole!
AND
Cefoxitin! (2nd gen)
Second generation cephalosporins good for?
Respiratory tract infections
H. Flu
Pneumococcus
First generation Ceph?
Good for
Staph aureus or Group A strep
What covers Pseudomonas?
- Ceftazidime and cefipime
- Ciprofloxacin
- aminoglycosides
- pep-tazo
- Meropenem
Gonorrhea normally covered by
Ceftriaxone
H flu covered by…
Cefuroxime and 3rd gen ceph
Traveler’s diarrhea think… 2 abx
- Azithro
2. Cipro
Macrolides and Cephalosporins do NOT cover
Enterococci
Azithromycin reserved for
Atypical bacteria
C. trachomatis
Ofloxacin