ABX Flashcards

1
Q

Broad spectrum PCN

A

Ampicillin

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2
Q

Interesting SE of ampicillin

A

Black tongue (thrush)

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3
Q

How is Ampicillin taken?

A

Empty stomach w/ water

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4
Q

Important Rx interactions w/ ampicillin?

A

Tetracycline - decreases the effectiveness

Allopurinol/Probencid - decreases elimination AND increases concentraion (effectiveness)

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5
Q

Which PCN combo is taken PO?

A

Amoxicillin/Clavulante

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6
Q

How is cefalozin taken?

A

With food

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7
Q

Purpose of cefalozin?

A

Presurgery Prophylaxis

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8
Q

Important Rx interactions w/ cefalozin?

A

Vancomycin and Aminoglycosides

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9
Q

What are alternatives to PCN allergies?

A

Impenem-Cilastatin
Vancomycin (PCN resistant)
Erythromycin

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10
Q

What class is cefalozin?

A

Cephalosporin

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11
Q

What class is Impenem-Cilastatin?

A

Carbapenems

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12
Q

Which Rx affect Liver Fx?

A

Impenem-Cilastatin

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13
Q

What class is Aztreonam?

A

Monobactams

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14
Q

Does Aztreonam work on GN or GP organisms?

A

GN and gentler on NF

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15
Q

Important Rx interactions w/ Aztreonam?

A

Aminoglycosides (Renal)

Furesemide (INC conc/effectiveness)

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16
Q

What class is gentamicin?

A

Aminoglycosides

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17
Q

Purpose of prescribing gentamicin?

A

Serious GN or anaerobic infections

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18
Q

Important gentamicin SE?

A

Ototoxic (permanent)

Nephrotoxic

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19
Q

Important RX interactions w/ gentamicin?

A

If combo w/ PCN - decrease dose
Vancomycin
Amphotercin B
Loop Diuretics

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20
Q

What class is Ciprofloxacin?

A

FLQ

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21
Q

What class is tetracycline hydrochloride?

A

Tetracyclines

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22
Q

What class is TMP-SMX?

A

Sulfonamides

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23
Q

What Rx is for anthrax infections/prophylaxis?

A

Ciprofloxacin

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24
Q

What Rx is associated with tendonitis/Achilles tendon rupture?

A

Ciprofloxacin

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25
Q

What Rx is associated with tooth discoloration?

A

Tetracycline hydrochloride

CI <8yo and PREG

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26
Q

What Rx is preferred for Pneumocystis Jiroveci (HIV inf)?

A

TMP-SMX

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27
Q

What medications are preferred for UTI’s?

A

TMP-SMX

Nitrofurantoin

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28
Q

What medications are CI for PEDS?

A

Ciprofloxacin (Not 1st L)
TMP-SMX (<2mo - kernictus)
Tetracycline Hydrochloride (Tooth discoloration)

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29
Q

What Rx prolongs QT Interval?

A

Ciprofloxacin

30
Q

What Rx if combined w/ another Rx requires ACHS?

A

TMP-SMX and Sulfonylureas

31
Q

What Rx is used to TXT uncomplicated UTI or prophylaxis for UTI’s?

A

Nitrofurantoin

32
Q

Which Rx is not ABX and is used for UTI pain relief?

A

Phenazopyridine

33
Q

What Rx is bacterial static?

A

Erythromycin

34
Q

What Rx is used for STI eye infections in newborns as an ointment?

A

Erythromycin

35
Q

What is erythromycin combined w/ to increase ability?

A

Streptomicin

36
Q

What Rx is ototoxic?

A

Gentamicin (IRREV)
Erythromycin (REV)
Vancomycin

37
Q

What Rx is associated with crystal build up and requires 1.5-3L of fluid?

A

TMP-SMX

38
Q

What is an important SE of TMP-SMX?

A

SJS

39
Q

What is an important SE of nitrofurantoin?

A

EKG - BBB - Wide QRS and ventricle issues

40
Q

What Rx decreases WBC/PLT?

A

Phenazopyririnde

41
Q

How is erythromycin taken?

A

Empty stomach with water

42
Q

What is an important RX combination that could cause cardiac arrest?

A

Erythromycin and Diltizam or Fluconazole

43
Q

What Rx is associated w/ disulfram reaction (ETOH)?

A

Metronidazole

44
Q

What Rx combination is associated with serotonin syndrome?

A

Linezolid

  • SSRI’s
  • MAOI’s
  • TCA’s
45
Q

What Rx is a first line C-Diff TXT?

A

Metronidazole - (1 dose prophylaxis if abdominal surgery occurs quickly)

46
Q

What Rx is extrapyridimal SE’s?

A

Metronidazole

47
Q

What Rx can cause redman syndrome?

A

Vancomycin

48
Q

What Rx can treat MRSA/VRE?

A

Linezolid

49
Q

What Rx combination can be used for C-Diff?

A

Metronidazole (IV) and Vancomycin (PO)

50
Q

What Rx can cause bone marrow suppression?

A

Linezolid

51
Q

What Rx is for nonresistant and active TB infections only?

A

Rifampin

52
Q

What Rx changes the colors of various body fluids?

A

Rifampin - Harmless

53
Q

What Rx can cause optic neuritis?

A

Ethambutol - visual acuity monitoring

54
Q

Which TB Rx is not hepatotoxic?

A

Ethambutol

55
Q

What TB Rx should be taken with vitamins?

A

Isoniazid - B6

56
Q

Which TB Rx causes a increasingly efficient liver?

A

Rifampin

57
Q

Do not give these RXN for PCN allergies…

A

PCN, Cephalosporins, and Carbapenems

58
Q

What monobactam is not cross sensitive with PCN?

A

Aztreonam

59
Q

S/S and Steven Johnson syndrome (SJS)?

A

Malaise, low fever

Rash to Slough

60
Q

What are S/S of redman syndrome?

A

Flush, HOTN
Rash
GIve >=60m diluted

61
Q

Four 1st line TB Rx?

A

Isoniazid
Rifampin
Pyrazinamide
Ethanbutol

62
Q

Four 2nd line TB Rx?

A

Levofloxacin (FLQ)
Moxifloxacin (FLQ)
Amikacin (Aminoglycoside)
Streptomycin (Macrolide)

63
Q

TXT recommendation for latent TB infection?

A

TXT -
1 Rx for 9mo OR
2 Rx for 3mo

64
Q

TXT recommendation for active TB infection?

A

TXT -
4 Rx for 2mo OR
2 Rx for 4mo

65
Q

Rx affecting liver Fx

A

Carbapenems,
Erythromycin,

Isoniazid,
Rifampin,
Pyrazinamide

66
Q

How to monitor LFTs?

A

Liver enzymes, TP, albumin, bilirubin

67
Q

How to monitor Renal Fx?

A

Titrate - Check I/O - labs (Cr/BUN/SG) - Fluids

68
Q

Rx causing C-Diff or yeast infections?

A

PCN, Cephs, Aztreonam, Tertacycline Hydrochloride, Erythromycin,

69
Q

Rx that interact w/ metalllics?

A

Ciprofloxacin,
Tertacycline Hydrochloride,
Erythromycin

70
Q

Rx that cause photosensitivity?

A

TMP-SMX,
Tertacycline Hydrochloride,
Ciprofloxacin