ABX Flashcards
Broad spectrum PCN
Ampicillin
Interesting SE of ampicillin
Black tongue (thrush)
How is Ampicillin taken?
Empty stomach w/ water
Important Rx interactions w/ ampicillin?
Tetracycline - decreases the effectiveness
Allopurinol/Probencid - decreases elimination AND increases concentraion (effectiveness)
Which PCN combo is taken PO?
Amoxicillin/Clavulante
How is cefalozin taken?
With food
Purpose of cefalozin?
Presurgery Prophylaxis
Important Rx interactions w/ cefalozin?
Vancomycin and Aminoglycosides
What are alternatives to PCN allergies?
Impenem-Cilastatin
Vancomycin (PCN resistant)
Erythromycin
What class is cefalozin?
Cephalosporin
What class is Impenem-Cilastatin?
Carbapenems
Which Rx affect Liver Fx?
Impenem-Cilastatin
What class is Aztreonam?
Monobactams
Does Aztreonam work on GN or GP organisms?
GN and gentler on NF
Important Rx interactions w/ Aztreonam?
Aminoglycosides (Renal)
Furesemide (INC conc/effectiveness)
What class is gentamicin?
Aminoglycosides
Purpose of prescribing gentamicin?
Serious GN or anaerobic infections
Important gentamicin SE?
Ototoxic (permanent)
Nephrotoxic
Important RX interactions w/ gentamicin?
If combo w/ PCN - decrease dose
Vancomycin
Amphotercin B
Loop Diuretics
What class is Ciprofloxacin?
FLQ
What class is tetracycline hydrochloride?
Tetracyclines
What class is TMP-SMX?
Sulfonamides
What Rx is for anthrax infections/prophylaxis?
Ciprofloxacin
What Rx is associated with tendonitis/Achilles tendon rupture?
Ciprofloxacin
What Rx is associated with tooth discoloration?
Tetracycline hydrochloride
CI <8yo and PREG
What Rx is preferred for Pneumocystis Jiroveci (HIV inf)?
TMP-SMX
What medications are preferred for UTI’s?
TMP-SMX
Nitrofurantoin
What medications are CI for PEDS?
Ciprofloxacin (Not 1st L)
TMP-SMX (<2mo - kernictus)
Tetracycline Hydrochloride (Tooth discoloration)