Absorprtion: Concentration vs Time Graphs Flashcards
1
Q
Where is concentration measured?
A
Systemic circulation
2
Q
What is the equation for concentration?
A
C= Mass/Volume
Mass: dose of drug (mg)
Volume: Plasma Vol (L, mL)
*Plasma volume ~ 2.5L
3
Q
What does the area under the curve (AUC) on the concentration vs time graph represent?
A
the amount of drug absorbed
4
Q
What is the equation for bioavailability?
A
B= AUC(po) / AUC(iv)
-largest bioavailability will have the largest area under the curve
