Aani Micro: Fever, Malaria etc Flashcards

1
Q

What temp etc would be considered pyrexia of unknown origin?

A

> 38.3 degrees

persisting for 3 weeks with no diagnosis despite treatment for 1 week

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2
Q

What do you do if a pt has febrile neutropenia?

A

MED EMERGENCY:
Take 2 culture samples then treat with Abx asap
Look for conditions that need neutrophils e.g. fungal/bacterial

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3
Q

If pt has PUO and is HIV positive- what are you thinking for the differentials?

A

TB
Kaposi’s sarcoma
PCP
CMV

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4
Q

What causes typhoid?

A

Samonella Typhi and Paratyphi

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5
Q

What are the key symptoms of typhoid?

A

Fever, abdo pain, diarrhoea
Headache
Hepatomegaly
ROSE SPOTS on abdo (in 30%)

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6
Q

What is the gram stain of typhoid?

A

Gram neg bacilli

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7
Q

Management of Typhoid?

A

Notifiable
Supportive (IV fluids)
Oral.IV Abx: IV Ceftriaxone

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8
Q

Examples of spotted fevers?

A

Rikettsia

Rocky Mountain

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9
Q

How do you pass on Rikettsia?

A

Zoonoses Via Tics/mites

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10
Q

Tx of spotted fevers?

A

IV Doxycycline

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11
Q

What are the different species that cause Malaria?

A

Plasmodium Falciparium
Plasmodium Vivax
Plasmodium Ovale
Plasmodium Malariae

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12
Q

In which organism’s infection would you found Schnuffner’s dots?

A

Plasmodium Ovale and Plasmodium Vivax

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13
Q

Describe the cell findings in P. Falciparum?

A

Ring forms (trophozoites) in RBCs and Banana/cresent gametocytes

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14
Q

How do you treat the differnt types of Malaria?

A

Falciparum: 600 mg Quinine 1 week then doxycycline/clindamycin
Vivax and Oval: Chloraquine then Primaquine

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15
Q

When can you not have Primaquine?

A

Pregnancy

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16
Q

How do you investigate for P.Falciparum malaria?

A

Thick blood film: will show parasites

Then thin blood film: will show type of malaria (in Falciparum will see ring trophzoites and Banana/cresent gametocytes)

17
Q

S/E of quinine?

A

Arrhythmias

18
Q

Treatment of mild/mod Falciparum?

A

PO 600mg Quinine TDS

Then Doxy and Clinda

19
Q

Treatment of severe Falciparum?

A

MEDICAL EMERGENCY

IV Artesenate AND quin/doxy/clin therapy

20
Q

Common symptoms of mild/mod malaria?

A

Fever
Rigors
Splenomegaly
Headache

21
Q

Symptoms of severe P.Falciparum malaria in adults?

A

AAB CRASH

ARDS
Acidosis
Bleeding

Consciousness impaired
Renal impairment
Anaemia
Shock
Hypoglycaemia