A1.2 Flashcards

Nucleic acids

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1
Q

What are nucleic acids?

A

The information molecules of cells which can be split into two types, deoxyribonucleic acid (DNA) or ribonucleic acid (RNA)

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2
Q

What is genetic code?

A

the code containing the information in the nucleic acids which is universal (in all organisms)

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3
Q

Where is DNA found?

A

chromosomes of the nucleus (and chloroplasts and mitochondria)

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4
Q

Where is RNA found?

A

in the cytoplasm and more specifically in the ribosomes

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5
Q

What is a nucleotide made of?

A

A nitrogenous base, a pentose sugar, a phosphate group

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6
Q

What are the 4 nitrogenous bases for DNA?

A

Adenine, thymine, cytosine and guanine

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7
Q

What reaction forms a nucleotide?

A

condensation reaction

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8
Q

What is the sugar phosphate backbone?

A

Alternating sugar and phosphate molecules, each base is attached to a pentose sugar that alternates with a phosphate molecule.

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9
Q

Where does the genetic code lie?

A

in the coding strand

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10
Q

How many different combinations are there?

A

64 (4x4x4)

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11
Q

What is a codon?

A

a three-letter or triplet code with each sequence standing for one of the 20 amino acids

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12
Q

What are the 4 nitrogenous bases for RNA?

A

adenine, uracil, cytosine, guanine

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13
Q

What are the 3 functional types of RNA?

A

Messenger RNA( mRNA), transfer RNA (tRNA) and ribosomal RNA (rRNA)

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14
Q

What is the bond in RNA formed between adjacent nucleotides called?

A

3’-5’ phosphodiester bond

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15
Q

How is RNA formed?

A

the condensation of nucleotide monomers

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16
Q

What is the DNA double helix?

A

two antiparallel polynucleotide strands paired together and held by hydrogen bonds

17
Q

What are the sections that code for proteins called?

A

genes

17
Q

What is a gene?

A

A heritable factor that influences a feature of an organism such as height

18
Q

Where are genes located?

A

each gene occupies a specific position on a chromosome hence each chromosome is a linear series of genes

19
Q

What is a locus?

A

the point where a gene for a particular characteristic is found every time

20
Q

What is an allele?

A

Each gene had two or more forms called alleles

21
Q

What is a homologous chromosome?

A

chromosomes of eukaryotic cells that occur in pairs

22
Q

What us complementary base pairing?

A

the combinations that fit together on the helix since they only form hydrogen bonds with each other, adenine and thymine, cytosine and guanine

23
Q

what are conserved sequences?

A

sequences that remain unchanged or only slightly changed

24
Q

What are the most highly conserved genes?

A

The ones that can be found in all organisms

25
Q

How is DNA packed into chromosomes?

A

by coiling the DNA double helix and looping it around protein beads called nucleosomes

26
Q

What is a nucleosome made of?

A

eight histone molecules make one bead

27
Q

What was the Hershey and Chase experiment?

A

an experiment to prove that DNA was the holder of information in the cell and not protein

28
Q

How did Hershey and chase conduct the experiment?

A

They labeled two different bacteriophages, one with DNA and one with protein and let them infect cultures of e coli. They observed that only the bacteriophage marked with DNA was transferred to the next generation