A&P Of The Cardiovascular System Flashcards
The ____ is the lowest part of the heart. Where is it located?
Apex
Located to the left of the 5th intercostal space and left mid clavicular line
What 3 layers of tissue make up the heart? These 3 layers are surrounded by a connective tissue sac known as the _____.
- Endocardium
- Myocardium (muscle)
- Epicardium
Surrounded by the PERICARDIUM
The _____ is the largest artery, supplying ____ blood to the _____.
AORTA
OXYGENATED
BODY
The ____ aorta passes through the thorax and becomes the ____ aorta as it passes through the abdomen.
THORACIC
AORTIC
What 2 areas of the body does the INFERIOR vena cava return venous blood from?
Viscera and lower extremities
What 3 areas of the body does the SUPERIOR vena cava return venous blood from?
Head, neck, and upper extremities
The inferior and superior vena cavas return ____ blood to the ____ of the heart.
DEOXYGENATED
RIGHT ATRIUM
Describe the flow of blood through the heart. (12)
- Inferior/superior vena cava
- Right atrium
- Tricuspid valve
- Right ventricle
- Pulmonic valve
- Pulmonary arteries
- Pulmonary veins
- Left atrium
- Bicuspid valve
- Left ventricle
- Aortic valve
- Aorta
What are the 3 main branches of the right coronary artery?
- Sinus node artery
- Right marginal artery
- Posterior descending artery
What are the 2 main branches of the left coronary artery?
- Circumflex artery
2. Left anterior descending artery
What artery supplies the right atrium?
Sinus node artery
What artery supplies the right ventricle?
Right marginal artery
What artery supplies the left atrium and left ventricle?
Left anterior descending artery
What 2 arteries supply the interventricular septum?
- Posterior descending artery
2. Left anterior descending artery
What 3 vessels make up the coronary venous circulation?
- Coronary sinus
- Cardiac veins
- Thebesian veins
What is the normal pacemaker of the heart?
Sinoatrial (SA) Node
What is intrinsic to the SA Node?
Cardiac automaticity
What 2 nerves converge to form the cardiac plexus at the base of the heart?
- Vagus nerve
2. Sympathetic cardiac nerves
The sympathetic influence is achieved by the release of _____ and _____.
Epinephrine
Norepinephrine
Sympathetic nerves stimulate the chambers of the heart to beat ____ ( ____ effect), and with ______ force of contraction ( ________ effect).
Faster (chronotropic effect)
Greater (inotropic)
The parasympathetic influence is achieved via _____ release from the _____ nerve.
Acetylcholine
Vagus
Parasympathetic nerves ___ the heart rate ( _____ effect) primarily through the influence of the ____.
Slow (chronotropic)
SA Node
What are baroreceptors?
Mechanoreceptors that detect change in pressure
What reflex is responsible for maintaining blood pressure?
Baroreceptor reflex
_____ baroreceptors are high pressure receptors and ____ receptors are low pressure receptors.
Arterial = high pressure Cardiopulmonary = low pressure
Baroreceptor reflex: What occurs during sympathetic activation that ultimately increases blood pressure?
Sympathetic activation leads to increased cardiac contractility, increased heart rate, venoconstriction and arterial vasoconstriction which elevates total peripheral resistance and cardiac output = increase in BP
Baroreceptor reflex: What occurs during parasympathetic activation that ultimately decreases blood pressure?
Parasympathetic activation leads to a decrease in heart rate and a small decrease in contractility = decrease in BP
The bainbridge reflex is also known as the _____ reflex.
ATRIAL
What is the bainbridge reflex? What does it inhibit?
An increase in HR due to an increase in central venous pressure which is detected by the stretch receptors in the right atrium.
Inhibits PARASYMPATHETIC ACTIVITY
Chemoreceptor reflex: Chemosensitive cells located in the ______ bodies and _____ body respond to changes in ___ status and blood oxygen tension.
Carotid bodies
Aortic body
pH status
Chemoreceptor reflex: At an arterial partial oxygen pressure of less than ____ mmHg or in conditions of ______, the chemoreceptors stimulate the _____ centers and _____ the depth and rate of _____. This activates the ______ system.
50 mmHg Acidosis Respiratory Increase Ventilation Parasympathetic
Chemoreceptor reflex: In the case of persistent ______, the CNS will be directly stimulated with a resultant increase in _____ activity.
Hypoxia
Sympathetic
What is a valsalva maneuver?
Forced expiration against a closed glottis
A valsalva maneuver results in an increase in _____ and _____ , and a decrease in _____, ______, AND ______.
Increase in INTRATHORACIC and CENTRAL VENOUS PRESSURE
Decrease in VENOUS RETURN, CARDIAC OUTPUT and BLOOD PRESSURE
What is atrial systole?
Contraction of the right and left atria pushing blood into the ventricles
What is atrial diastole?
The period between atrial contractions when the atria are repolarizing
What is ventricular systole?
Contraction of the ventricles pushing blood into the pulmonary arteries and the aorta
What is ventricular diastole?
Period of relaxation between ventricular contraction when the ventricles are repolarizing
What is preload? What does it reflect?
Refers to the tension in the ventricular wall at the end of diastole. It reflect the venous filling pressure that fills the left ventricle during diastole.
What is afterload?
Refers to the forces that impede the flow of blood out of the heart, primarily the pressure in the peripheral vasculature of the compliance of the aorta, and the mass and viscosity of blood
What is stroke volume (SV)? What is the normal range of SV?
The volume of blood ejected by each contraction of the left ventricle.
Normal SV ranges from 60 to 80 ml depending on age, sex, and activity.
What is cardiac output?
The amount of blood pumped from the left or right ventricle per minute.
Cardiac output is equal to the product of _____ and _____.
Stoke volume x heart rate = cardiac output
Normal CO for an adult male at rest is ____ to ____ L/min with women producing slightly ____.
4.5-5.0 L/min
LESS
Cardiac output can increase up to ____ L/min during exercise.
25 L/min
What is venous return? Venous return must equal _____ when averaged over time.
The amount of blood that returns to the right atrium each minute.
CARDIA OUTPUT (because the heart is a closed loop)
The _____ are responsible for carrying oxygenated blood to the body and the ___ are responsible for returning deoxygenated blood back to the heart.
Arteries
Veins
What is the normal blood volume of an adult male?
4.5-5.0 mL
Women slightly less
What is hypovolemia?
Decreased blood volume
List 6 causes of hypovolemia.
- Dehydration
- Diarrhea
- Sweating
- Severe burns
- Bleeding
- Diuretic medication used to treat HTN
List 3 symptoms of hypovolemia.
- Orthostatic hypotension
- Tachycardia
- Elevated body temperature
What is hypervolemia?
Fluid overload; increase in blood plasma
What are 2 causes of hypervolemia?
- Excess fluid intake (IV or blood transfusions)
2. Fluid retention
List 3 signs and symptoms of hypervolemia.
- Swelling in the legs
- Ascites
- Fluid in the lungs
What is plasma? Plasma is important for regulating ____ and ____.
Liquid component of blood in which the blood cells and platelets are suspended.
Regulates BLOOD PRESSURE and TEMPERATURE
______ is the protein that enables blood to bind to oxygen.
Hemoglobin
_____ is the condition that occurs when the number of red blood cells is too low leading to fatigue and weakness.
Anemia
_____ is the condition that occurs when the blood is too thick, increasing the risk of stroke or heart attack.
Polycythemia
______ assist in clotting by clumping together at the bleeding site.
Platelets
What 2 conditions can occur as a result of having too low or too high number of platelets?
Too low = thrombocytopenia (bruising and abnormal bleeding)
Too high= thrombocythemia (thrombosis leading to increased risk for MI and stroke)
An increase in _____ may indicate leukemia.
White blood cells (leukocytes)
List 5 main types of WBCs and their functions.
- Neutrophils: protect the body against infection my ingesting bacteria and debris
- Lymphocytes: T lymphocytes and natural killer cells protect against viral infections and destroy cancer cells; B lymphocytes develop into cells that produce antibodies
- Monocytes: ingest dead or damaged cells
- Eosinophils: kill parasites, destroy cancer cells, and are involved in allergic responses
- Basophils: participate in allergic reactions