9 - Mucosal colour changes Flashcards

1
Q

What are the causes of oral white lesions?

8

A
  • hereditary
  • smoking
  • frictional
  • lichen planus
  • candidal leukoplakia
  • carcinoma
  • GVHD
  • lupus erythematous
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2
Q

Why are white lesions white?

A
  • tissues have normal pink colour from connective tissue and blood vessels
  • increase in keratin thickness makes the tissue more opaque and presents as white
  • less blood in the tissues presents as white
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3
Q

Define leukoplakia.

A
  • a white patch that cannot be scraped off or attributed to any other cause
  • diagnosis of exclusion
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4
Q

What causes frictional keratosis?

A

Parafunction, thickening of the keratin layer of the mucosa

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5
Q

What causes smokers keratosis?

A

Thermal trauma from the smoke causing thickening of the keratin layer of the mucosa

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6
Q

What is hereditary keratosis?

A
  • know as white sponge naevus
  • white lesions found in areas of mucosa not subject to trauma
  • fluid accumulates between layers of epithelium
  • begins in childhood
  • runs in families
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7
Q

What can cause a chemical burn to the mucosa?

2

A
  • aspirin
  • alendronic acid
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8
Q

What causes hairy leukoplakia?

A

EBV

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9
Q

Describe pseudomembranous candidiasis.

A
  • white patches that can be scraped off mucosa
  • known as thrush
  • can bleed under where white patches were present due to inflammation
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10
Q

When should you refer a white lesion?

A
  • if the lesion is red and white, focus on red lesion when deciding to refer
  • is lesion is raised and thickened
  • if the lesion appears to have no cause
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11
Q

What areas are of concern when a white patch appears?

3

A
  • lateral tongue
  • anterior FOM
  • soft palate
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12
Q

Why do red lesions present red?

A
  • increased blood flow through inflammation or dysplasia
  • reduced thickness of epithelium
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13
Q

Define erythroplakia.

A
  • unexplained red change that cannot be attributed to any other cause
  • requires biopsy due to malignancy concern
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14
Q

Why are lesions red/blue?

A
  • dark = slow moving blood
  • light = clear fluid, saliva or lymph
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15
Q

What is a haemangioma?

A
  • red lesion commonly found on the side of the tongue
  • vascular so can increase in size and shrink
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16
Q

What is a lymphangioma?

A

Cavernous vesicle commonly found on tongue

17
Q

What vasculitic diseases can present with erythematous lesions?

4

A
  • giant cell arteritis
  • polyarteritis nodosa
  • kawasaki disease
  • granulomatosis with polyangiitis
18
Q

Why are some lesions pigmented?

A
  • exogenous (coffee, chlorhexidine, bacterial overgrowth)
  • intrinsic (racial, melanotic macule, melanoma, melanocytic naevus)
  • foreign body (amalgam)
19
Q

Define melanotic macule.

A
  • freckle
  • one melanocyte produces excess melanin
20
Q

Define melanocytic naevus.

A

Too many melanocytes in one area producing normal amounts of melanin

21
Q

What are the signs of melanoma?

A
  • variable pigmentation
  • irregular outline
  • raised surface
  • symptomatic (itchy or bleeding)