7 - Therapeutic drug use in oral medicine Flashcards
1
Q
What can be used for non-steroidal topical treatment of oral mucosal lesions?
A
- chlorhexidine mouthwash (dilute 50% with water)
- benzdamine mouthwash/spray
- OTC remedies (bonjela, listerine)
2
Q
What can be used for steroidal topical treatment of oral mucosal lesions?
A
- hydrocortisone mucoadhesive pellet
- betamethasone mouthwash
- beclomethasone MDI
3
Q
How do you use beclomethasone MDI for oral mucosal lesions?
A
- position exit vent directly over ulcer
- 2 puffs to mucosa
- 2-4 times daily
- don’t rinse
4
Q
How do you use betamethasone mouthwash for oral mucosal lesions?
A
- 2 x 0.5mg betnesol tablets to 10ml water
- 2 mins rinsing x 2 daily
- do not swallow
- do not eat/drink 30 mins after use
5
Q
What are the systemic risks of using steroids?
A
- adrenal suppression and steroid dependency
- cushingoid features
- osteoporosis risk
- peptic ulcer risk
- mood/sleep alteration
6
Q
What immune suppressants are used systemically in oral medicine?
A
- hydroxychloroquine (lichen planus)
- azathioprine
- mycophenolate
7
Q
What immunotherapy drugs are used systemically in oral medicine?
A
- adalimumab
- enterecpet
8
Q
What checks must be done prior to starting a patient on a systemic immunomodulatory therapy?
9
A
- BBV screen
- chest x-ray
- cervical smear
- EBV
- FBC
- Us and Es
- liver function
- pregnancy test
- zoster antibody screen
