8 -- bacterial virulence Flashcards

1
Q

adhesin

A

enables binding of organisms to host tisue

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2
Q

invasin

A

enables the organism to invade a host cell

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3
Q

impedin

A

enables the organism to avoid host defense

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4
Q

aggressin

A

causes damage directly

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5
Q

modulin

A

induces damage indirectly

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6
Q

microbiology of skin is typically gram -ve

A

false

usually thicker (gram +) but certain areas are gram -ve

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7
Q

in scalded skin syndrome, what is not formed which leads to the exfolliative toxin?

A

`bridges are missing

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8
Q

where does a superantigen bind>

A

not as MHC class II area, but instead joins adjacent to the binding site

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9
Q

diagnostic criteria for toxic shock syndrome

A

fever
diiffuse macular erythroderma (sunburn)
hypotension

> 3 organ systems involved (liver,blood,renl,mucous membranes, GI ,muscular, CNS)

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10
Q

adhesins work through extra cellular matrix molecues, where are these present?

A

endothelial, epithelial, blood clots

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11
Q

necrotizing pneumonia cannot be treated using antibiotics as

A

immune system is dysfunctional and so will not clear the antigen

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12
Q

type of skin conditions associated with strep pyogenes

A

impetigo
cellulitis
erysipelas
necrotizing fascitis

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