8 -- bacterial virulence Flashcards
adhesin
enables binding of organisms to host tisue
invasin
enables the organism to invade a host cell
impedin
enables the organism to avoid host defense
aggressin
causes damage directly
modulin
induces damage indirectly
microbiology of skin is typically gram -ve
false
usually thicker (gram +) but certain areas are gram -ve
in scalded skin syndrome, what is not formed which leads to the exfolliative toxin?
`bridges are missing
where does a superantigen bind>
not as MHC class II area, but instead joins adjacent to the binding site
diagnostic criteria for toxic shock syndrome
fever
diiffuse macular erythroderma (sunburn)
hypotension
> 3 organ systems involved (liver,blood,renl,mucous membranes, GI ,muscular, CNS)
adhesins work through extra cellular matrix molecues, where are these present?
endothelial, epithelial, blood clots
necrotizing pneumonia cannot be treated using antibiotics as
immune system is dysfunctional and so will not clear the antigen
type of skin conditions associated with strep pyogenes
impetigo
cellulitis
erysipelas
necrotizing fascitis