7.5 chromosomal Abnormality Flashcards

1
Q

Incorrect number of chromosomes

A
  • nondisjunction
    (chromosomes don’t separate properly during meiosis)
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2
Q

Breakage of chromosomes

A
  • deletion
  • duplication
  • inversion
  • translocation
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3
Q

nondisjunction

A

chromosomes do not separate properly.
meiosis 1- homologous chromosomes do not separate properly
meiosis 2- sister chromatids fail to separate during

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4
Q

What fails to separate if nondisjunction occurs in Meiosis 1?

A

homologous chromosomes

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5
Q

What is the result for the gametes? Their future zygotes?

A

Gametes would be missing a chromosome or have an extra- zygotes would be diploid except for extra or missing chromosome.

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6
Q

What fails to separate if nondisjunction occurs in Meiosis 2?

A

sister chromatids

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7
Q

What is the result for the gametes? Their future zygotes?

A

Gametes could be normal, or would be missing a chromosome or have an extra- zygotes could be normal or would be diploid except for extra or missing chromosome.

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8
Q

Nondisjunction results in

A

Offspring with wrong chromosome number

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9
Q

Trisomy

A

cells are diploid except they have 3 copies of one chromosome type

2n+1

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10
Q

Monosomy

A

cells are diploid except they have only one copy of a chromosome

2n-1

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11
Q

deletion

A

gamete= missing gene
zygote= missing gene, only 1 instead of 2

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12
Q

duplication

A

gamete= extra gene
zygote= extra gene, 3 instead of 2

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13
Q

inversion

A

gamete= could be normal
zygote= might have trouble pairing chromosomes for meiosis

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14
Q

translocation

A

gamete= could be normal , could be missing or extra genes
zygote= depends on which chromatids end up

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