7 — Radiation biophysics, dosimetry, biological effect of radiations Flashcards
What is the biological effect of radioactive radiation based on?
What kind of particles are able to produce a biological effect in radiation biology?
What is a hit in radiation biology?
How can a dose-response curve be constructed?
What is the probability of generating exactly ‘n’ hits when applying a dose of D in volume V?
How does the number of ionizations depend on the dose of the radiation?
Write the equation describing the dose-response curve when one hit is necessary for inactivation?
What is D37?
What is the principle of the indirect action of radiation?
What kind of products are capable of damaging biological objects arise during irradiation of aqueous solutions?
What is the definition of absorbed dose?
Define the unit of equivalent dose.
Define effective dose. Why is it necessary to introduce effective dose when examining radiation damage in biological organisms?
List the physical factors influencing radiation sensitivity.
What is the smallest dose which can produce a biological effect?
How can radioactive radiation cause a double strand break in DNA?
Write the equation describing cell survival according to the linear-quadratic model.
In which part of the cell cycle are cells the most and the least sensitive to radioactive radiation?
How does radiosensitivity change as a function of the level of oxygenation?
How and why does fractionation of radioactive radiation influence the radiation sensitivity of cells?
