7. Poly- und Dermatomyositis Flashcards

1
Q

(PM/DM)

Assoziation

A

mit Tumoren

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2
Q

(PM/DM)

PM: Symptome (2)

A
  • Muskelschmerzen
  • proximale Muskelschwäche an Schulter- und Beckengürtel (bis hin zu proximal betonter Tetraparese)
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3
Q

(PM/DM)

DM: Prädilektionsstellen (2)

A
  • Gesicht
  • Hand
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4
Q

(PM/DM)

Befunde im Gesicht (2)

A
  • periorbitales Ödem
  • hellrotes bis bläulich-rotes Erythem
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5
Q

(PM/DM)

pathognomonisch

A

heliotropes Erythem

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6
Q

(PM/DM)

heliotropes Erythem: Lokalisation

A

Augenlider

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7
Q

(PM/DM)

Befunde in Händen (2)

A
  • Gottron-Zeichen
  • Gottron-Papeln
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8
Q

(PM/DM)

Gottron-Zeichen

A

schuppende Erytheme an den Fingergelenken

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9
Q

(PM/DM)

Gottron-Papeln: Lokalisation

A

über MCP- und DIP-Gelenken der Fingerstreckseiten

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10
Q

(PM/DM)

Labor: Diagnosesicherung

A

AK-Serologie

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11
Q

(PM/DM)

AK-Serologie (2)

A
  • unspezifisch aber häufig
  • spezifisch aber selten
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12
Q

(PM/DM)

Labor: Erhöhung von … (4)

A
  • CK
  • Myoglobin
  • AST
  • LDH
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13
Q

(PM/DM)

unspezifischer AK

A

ANA

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14
Q

(PM/DM)

spezifische AK (3)

A
  • Mi-2-AK
  • anti-Jo-1
  • anti-TIF-gama-AK
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15
Q

(PM/DM)

apparative Diagnostik (3)

A
  • MRT
  • EMG
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16
Q

(PM/DM)

Diagnostik: Goldstandard

A

Biopsie

17
Q

(PM/DM)

Initialtherapie

A

Glucocorticoide

18
Q

(PM/DM)

Erhaltungstherapie

A

Glucocorticoide ausschleichen

19
Q

(PM/DM)

Langzeittherapie: 1. Wahl

A

AZA