2. Rheumatoide Arthritis Flashcards

1
Q

(RA)

Hauptrisikofaktor

A

Rauchen

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2
Q

(RA)

Sonderformen (2)

A
  • Zervikalarthritis
  • Felty-Syndrom
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3
Q

(RA)

Zervikalarthritis: Komplikationen (2)

A
  • atlantoaxiale Instabilität
  • zervikale Myelopathie
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4
Q

(RA)

Felty-Syndrom: Komplikationen

A
  • Granulozytopenie
  • Splenomegalie
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5
Q

(RA)

ACR/EULAR Klassifikationskriterien (4)

A

1- geschwollene/schmerzhafte Gelenke

2- Serologie

3- akute-Phase-Parameter

4- Symptomdauer
4-

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6
Q

(RA)

Serologie (2)

A
  • RF
  • ACPA
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7
Q

(RA)

akute-Phase-Parameter: Spezifität

A
  • RF: niedrige
  • ACPA: sehr hohe
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8
Q

(RA)

akute-Phase-Parameter (2)

A
  • CRP
  • BSG
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9
Q

(RA)

Leitsymptome (2)

A
  • Morgensteifigkeit
  • symmetrische Polyarthritis
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10
Q

(RA)

Symptomdauer

A

> 6 Wochen

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11
Q

(RA)

Prädilektionsstellen (3)

A
  • MTP
  • MCP
  • PIP
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12
Q

(RA)

andere Symptome (3)

A
  • Keratoconjunctivitis sicca
  • Lungenfibrose
  • Bursitis
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13
Q

(RA)

Befunde (3)

A
  • Deformitäten
  • Gaenslen-Zeichen
  • Rheumaknoten
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13
Q

(RA)

Deformitäten (3)

A
  • Knopfloch
  • Schwanenhals
  • 90-90
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13
Q

(RA)

Laborbefunde (4)

A
  • erhöhtes Ferritin
  • Leukozytose
  • Thrombozytose
  • normo- oder mikrozytäre Anämie
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13
Q

(RA)

Bildgebung der Wahl

A

Röntgen der Hände und Füße

14
Q

(RA)

symptomatische Therapie

A

NSAR

15
Q

(RA)

DMARD: Mittel der Wahl

A

MTX

15
Q

(RA)

Gaenslen-Zeichen

A

Kompressionsschmerz der Hand (oder des Fußes) auf Höhe der Fingergrundgelenke bei Querdruck

16
Q

(RA)

kurative Therapie: Möglichkeiten

A
  • DMARD

+ bDMARD oder tsDMARD

17
Q

(RA)

bDMARD: Mittel der Wahl

A

TNF-alpha

18
Q

(RA)

tsDMARD: Mittel der Wahl

A

JAK-Inhibitoren