14. Antiphospholipid Syndrom Flashcards by Ian Paglione | Brainscape

Q

(APS)

Pathophysiologie

A

systemische Autoimmunerkrankung

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Q

(APS)

Ätiologie (2)

A

primär
sekundär (meist Patienten mit SLE)

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Q

(APS)

Diagnosekriterien (2)

A

mind. 1 klinisches Kriterium
mind. 1 Laborkriterium

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Q

(APS)

Primärprophylaxe

A

ASS 100 mg/d

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Q

(APS)

klinische Kriterien (2)

A

arterielle oder venöse Thrombosen
Komplikationen in der Schwangerschaft

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Q

(APS)

Laborkriterien (3)

A

Lupus-Antikoagulanz (LA)
anti-Cardiolipin-AK (aCL)
anti-Beta2-Glykoprotein-I-AK (anti-Beta2-GPI)

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Q

(APS)

Sekundärprophylaxe

A

orale Antikoagulation

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Q

(APS)

orale Antikoagulation: Möglichkeiten (2)

A

Vit-K-Antagonisten

oder

Heparine

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Q

(APS)

orale Antikoagulation: INR-Zielwert

A

2-3

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