4. systemische Sklerose Flashcards

1
Q

(SSc)

CREST-Syndrom

A

C: Calcinosis cutis

R: Raynaud-Syndrom

E: Ösophageal Hypomotilität

S: Sklerodaktylie

T: Teleangiektasien

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1
Q

(SSc)

Einteilung (2)

A
  • diffuse (Dc)
  • limitierte (Lc): CREST-Syndrom
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2
Q

(SSc)

Manifestationen (2)

A
  • kutane
  • extrakutane
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3
Q

(SSc)

kutane Manifestationen: Lokalisationen (2)

A
  • Finger (Sklerodaktylie)
  • Gesicht
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4
Q

(SSc)

Sklerodaktylie: Befunde (2)

A
  • Fingerkruppennekrose
  • Madonnenfinger
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5
Q

(SSc)

extrakutane Manifestationen (3)

A
  1. Gastrointestinaltrakt
  2. Lunge
  3. Nieren
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6
Q

(SSc)

Befund im Gesicht

A

Tabaksbeutelmund

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7
Q

(SSc)

extrakutane Manifestation im Gastrointestinaltrakt

A

Hypomotilität des Ösophagus oder des Dünndarms

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8
Q

(SSc)

extrakutane Manifestationen in den Lungen (2)

A
  • Lungenfibrose
  • pulmonale Hypertonie
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9
Q

(SSc)

extrakutane Manifestationen in den Nieren (2)

A
  • Niereninsuffizienz
  • aHT
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10
Q

(SSc)

Labor

A

Serologie

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11
Q

(SSc)

Serologie bei allen Fällen

A

ANA (antinukleäre AK)

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12
Q

(SSc)

Serologie bei LcSSc

A

ACA (antizentromere AK)

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12
Q

(SSc)

Serologie bei DcSSc

A

Anti-Scl-70 (anti-Topoisomerase I)

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13
Q

(SSc)

Anti-Scl-70 (anti-Topoisomerase I): Prognose

A

schlechtere

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14
Q

(SSc)

Bildgebung

A

Röntgen der Hände

15
Q

(SSc)

Röntgen: Befund

A

gelenkenahe Akroosteolysen

16
Q

(SSc)

Therapie

A

Glucocorticoide