7 mass transport Flashcards
describe the structure of haemoglobin
quaternary structure
4 sub units containing a haem group
what can each haem group do on a haemoglobin molecule?
combine with one molecule of oxygen
what is oxyhaemoglobin?
haemoglobin that is associated with oxygen
what is deoxyhaemaglobin?
haemoglobin that is dissociated with oxygen
how do you calculate percentage saturation of haemoglobin with oxygen?
oxygenated haemoglobin / maximum saturation x100
define partial pressure of oxygen
the amount of oxygen in a mixture of gases
what does affinity mean?
a natural attraction
why does a high ppCO2 cause a lower affinity to O2?
CO2 makes blood acidic which lowers the pH and changes Hb tertiary structure
what is the role of Hb?
to transport oxygen
what are the 4 chambers of the heart called?
right atrium
right ventricle
left atrium
left ventricle
what are the 4 main vessels called in the heart?
vena cava
pulmonary artery
pulmonary vein
aorta
do veins carry blood in or out of the heart?
in
what are the 2 valves called?
semi lunar
atrio ventricular
when do semi lunar valves open?
when there is a greater pressure in the ventricle
when do valves open?
when pressure is higher behind valve
why do valves open and close?
to prevent back flow of blood
what does the septum do in the heart?
separate deoxygenated and oxygenated blood
what are the three stages of the cardiac cycle?
atrial systole
ventricular systole
diastole
what do systole and diastole mean?
systole- contraction of heart muscle
diastole- relaxed heart muscle
what is the activity of the heart measured as?
cardiac output
define cardiac output
volume of blood pumped out of left ventricle per minute
what are four risk factors of coronary heart disease?
high cholesterol
high lipid diet
lack of exercise
smoking
what is the structure of an artery?
endothelial layer: thin to reduce friction
elastic layer: thick
outer layer: made of fibrous proteins for strength
what is the structure of a capillary?
only has single endothelial layer