7: Gram Negative Bacteria Flashcards

1
Q

Specific plate and agar for growing Neisseria

A

“Chocolate agar” (heated blood), on Thayer-Martin agar (VCN Abx modified)

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2
Q

Two Neisseria meningitis vaccines and what groups they target

A
  1. MenACWY: preteens and teens

2. MenB: 16-18 year olds

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3
Q

PID

A

Pelvic inflammatory disease; infection of uterus, Fallopian tubes, and ovaries - can cause sterility

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4
Q

Enterics

A

Gram negative bacteria that are part of the normal GI flora or cause GI disease

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5
Q

Three bacterial mechanisms that cause different types of diarrhea

A
  1. Lack of invasion -> watery diarrhea
  2. Epithelial invasion -> blood diarrhea, fever, cramps
  3. LN and blood stream invasion -> diarrhea +/- blood, fever, abdominal pain -> sepsis
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6
Q

Agar used to see if bacteria ferments lactose and what color it changes

A

MacConkey agar -> turns pink

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7
Q

What do ETEC, EIEC, EHEC, and HUS stand for?

A
  1. ETEC: Enterotoxigenic E. coli
  2. EIEC: enteroinvasive E. Coli
  3. EHEC: enterohemorrhagic
  4. HUS: hemolytic uremic syndrome
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8
Q

Most common cause of UTIs

A

E. coli

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9
Q

Most common species of Shigella in the US

A

Shigella sonnei

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10
Q

Explain Typhoid Mary

A

Typhoid fever can have a asymptomatic chronic carrier state - Typhoid Mary was an asymptomatic cook in the 1900’s

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11
Q

What does urease do?

A

Breaks down urea -> CO2 + ammonia

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12
Q

Susceptible individuals to pseudomonas aeruginosa

A

CF, burn victims, hospitalized pts, diabetics

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13
Q

Reiter’s Syndomre: describe

A

A post-infectious immune mediated reaction, AKA reactive arthritis

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14
Q

Gene associated with Reiter’s syndrome

A

HLA-B27

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15
Q

Classic triad of Sx in Reiter’s syndrome

A

Conjunctivitis, urethritis, arthritis

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16
Q

What type of bacteria triggers Retier’s syndrome and name examples

A

Enteric bacteria: salmonella, shigella, c. Jejuni, yersinia enterocolitica, c. Diff

17
Q

Hib vaccine

A

Against Haemophilus influenzae, given in first 1.5 yrs of life

18
Q

Three zoonotic bacilli that are intracellular organisms

A

Yersinia pestis, francisella tularensis, brucella

19
Q

Size of chlamydia sp

A

Very small, on the order of viruses

20
Q

How many women are asymptomatic with chlamydia

A

About 3/4 of women

21
Q

Weil-Felix test positive

A

Shows agglutination by OX Abs

22
Q

Which species are mostly Weil-Felix positive?

A

Rickettsia

23
Q

Two types of screening for syphilis

A

VDRL, RPR

24
Q

What does it mean if a bacterium is acid fast?

A

Has a waxy cell wall with mycolic acids which retain stain after treatment, so they look gram negative but are actually gram positive

25
Q

What causes granulomas in mycobacterium infections?

A

Cell mediated immunity

26
Q

Major virulence factor for mycobacterium

A

Mycosides

27
Q

Smallest species of bacteria

A

Mycoplasma pneumoniae

28
Q

Diagnostic test for mycoplasma pneumoniae

A

Cold agglutinins

29
Q

Which type of E. Coli is E. Coli 0157?

A

HUS: Hemolytic uremic syndrome