7 - Development of Great Vessels Flashcards
Development of the Arterial System
1st month to 1st breath
Occurring at the same time with
expanding rest of body vessels
Aortic Arches: Arise from the
aortic sac
Aortic Arches: Terminate in the
right & left dorsal aortae
Aortic Arches: Appear in a
cranial to caudal sequence & not all simultaneously
Aortic Arches:
Aortic arch arteries, pharyngeal arch arteries and branchial (gill) arch arteries are all synonyms
Note: right & left dorsal aortae fuse into a
single vessel from 4th thoracic region to 4th lumbar region
1st arch
Regress – maxillary a.
2nd arch
Regress – stapedial & hyoid aa.
3rd arch
L/R common carotid, internal carotid, & external carotid aa.
4th arch
Left: Part of aortic arch
Right: Part of the r. subclavian a.
6th arch
Left: L. pulmonary a. & ductus arteriosus
Right: R. pulmonary a.
7th segmental artery
Left: L. subclavian a.
Right: Part of r. subclavian a.
Dorsal aorta
Left: Descending thoracic aorta
Right: Regress – part of r. subclavian a.
Aortic sac*
Left: Part of aortic arch
Right: Brachiocephalic trunk
Note that the arteries arising from the first three pairs of aortic arch arteries are
bilateral, whereas vessels derived from arches four and six develop asymmetrically
Also note the aortic sac will form
right and left horns which will subsequently form the left/right adult derivatives
Sixth arch is known as the
pulmonary arch.
7th segmental artery will form the whole
left subclavian artery and part of the right subclavian
Note the aortic sac forms
right and left horns which will subsequently form the left/right adult derivatives
Part of right dorsal aorta
disappears
Heart moves into thoracic cavity; carotid & brachiocephalic aa. elongate; left subclavian shifts position
Course of recurrent laryngeal nn. becomes different on right and left
Most somatic arteries of trunk develop from
intersegmental arteries from dorsal aorta
Develop:
Intercostal aa.
Lumbar aa
Vitelline Artery: Initially are number of
paired vessels supplying the yolk sac
Will fuse to form arteries in dorsal mesentery of the gut
Vitelline Artery: Develop into:
Celiac a. (trunk)
Superior mesenteric a.
Umbilical Artery: Initially are paired
ventral branches off dorsal aorta; course to the placenta
Umbilical Artery: Develop into:
Inferior mesenteric a.
Umbilical Artery: During week 4 also forms
secondary connection with dorsal aorta
Common iliac a.
Umbilical Artery: After birth, proximal portions persist as
internal iliac & superior vesical aa.
Distal parts are obliterated to form the median umbilical ligaments
Intersegmental arteries
derivatvies
Intercostal arteries
Lumbar arteries
Vitelline arteries
derivatvies
Celiac trunk
Superior mesenteric artery
Umbilical arteries
derivatvies
Inferior mesenteric artery
Common iliac artery
Proximal portion - Internal iliac artery & superior vesical artery
Distal portion – Medial umbilical ligaments
Umbilical arteries
derivatvies
Inferior mesenteric artery
Common iliac artery
Proximal portion - Internal iliac artery & superior vesical artery
Distal portion – Medial umbilical ligaments
Great vessels derived from
Derived from epicardium
Connection to the aorta is formed by
ingrowth of arterial endothelial cells
This is how the coronary aa. “invade” the aorta
Embryonic Venous System: 3 pairs of
major veins
All three systems are initially bilaterally symmetrical and converge on the right and left sinus horns of the sinus venosus. However, the shift of the systemic venous return to the right atrium initiates a remodeling that reshapes these systems to yield the adult patterns.
Embryonic Venous System: Vitelline veins
Drains GI tract & gut derivatives
Embryonic Venous System: Umbilical veins
Oxygenated blood from placenta to embryo