6.4 Gas Exchange Flashcards
Why do we need a ventilation system?
We are large organisms. Oxygen cannot diffuse into all our cells directly from the air, nor can waste products be directly ejected from the body. We have specialized organ systems, which are efficient but need delivery of nutrients and removal of waste. The ventilation system ensures the blood can be the medium for this.
We are land-borne. Gases need moist surfaces (membranes) in order to diffuse. Our lungs are moist membranes, allowing oxygen to diffuse into the blood and carbon dioxide to diffuse out.
The ventilation system maintains a large concentration gradient between the alveoli and the blood. The constant flow of past the alveoli brings blood with a high CO2 concentration and low O2 concentration. Breathing out keeps the CO2 concentration in the alveoli low, so it diffuses out of the blood. Breathing in keeps O2 concentration in the alveoli high, so it diffuses into the blood.
Gas exchange
For gas exchange to be efficient at the lungs, high concentration gradients must be maintained in the alveoli
Breathing in increases the concentration gradient of O2 between the alveoli and the blood – so it diffuses into the blood
Breathing out increases the concentration gradient of CO2 between the blood and alveoli – so it diffuses out of the blood
If the alveoli were not ventilated, equilibrium would be reached, and no gas could be exchanged
Alveoli purpose
Alveoli increase surface area for gas exchange.
Each with their own network of capillaries
Along with ventilation, a constant supply of fresh blood helps to maintain the concentration gradient of O2 and CO2
Type I pneumocytes
Single layer of epithelium cells
Flattened cells, 0.15μm thick
Type I pneumocytes
How do these features help facilitate gas exchange?
Capillaries also only one cell-thick
Very small distance for O2 and CO2 to travel during gas exchange
Type II pneumocytes
Rounded cells that make up 5% of alveolar surface
Secrete fluid that coats inner surface of alveoli
Fluid contains surfactant
Surfactant reduces surface tension and prevents fluid from causing the sides of alveoli from adhering to each other
Helps prevent collapse of lung
Premature babies can suffer from insufficient pulmonary surfactant
Type II pneumocytes
How does this feature help facilitate gas exchange?
Moisture aids in diffusion of gases
Trachea
rings of cartilage
Keep open even in low pressure
Bronchi
rings of cartilage
Bronchioles
smooth muscle fibres in walls
Allows width of airways to change
Diaphragm
controls volume of chest cavity
Alveoli
gas exchange
Contracting muscles do work –
get shorter
Relaxing muscles do no work –
lengthen passively
Muscles can only move in one direction –
so moving in two directions requires two muscles that alternate between relaxing/contracting – antagonistic pairs