6.2 Mitosis Flashcards
What is mitosis
Division of the nucleus
What is the purpose of mitosis
Ensures when a parent cell divides both daughter cells are identical
What is initial the role of chromosomes in mitosis
Each chromosome is converted into two identical chromatids. These chromatids are then joined together in a region called the centromere.
Why is it important to keep the two chromatids together
So that they can be precisely manoeuvred and segregated equally, one into each of the two new daughter cells
What are the 4 stages of mitosis
Prophase, metaphase, anaphase and telophase
How can you view each stage of mitosis
Using a light microscope
What happens during prophase
- Chromatin fibres begin to coil and condense to from chromosomes
- The nucleolus disappears and the nuclear membrane begins to break down
- Protein microtubules form spindle shaped structures that link the poles of the cell
- The two centrioles migrate to opposite poles of the cell
- Spindle fibres attach to specific to specific areas on the centrometeres and start to move the chromosomes
to the centre of the cell - By the end of prophase the nuclear envelope has disappeared
What is the role of the nucleolus
RNA synthesis
What are chromatin fibres
Complexes made up of various protiens, RNA and DNA
What is the role of the spindle fibres
To move the chromosomes into the correct positions before division
What are centrioles
Cylindrical bundles of proteins that help in the formation of the spindle
What happens during metaphase
Chromosomes are moved by the fibres to form a plane in the centre of the cell, caled the metaphase plate
What happens during anaphase
The centrometres holding the pairs of chromatids together in each chromosome divide. Chromatids are separtated and pulled to opposite poles of the cell.
What happens during telophase
The chromatids have reached the poles and are now called chromosomes. The two new sets of chromosomes assemble at each pole and the nuclear envelope reforms around them. Chromosomes begin to uncoil and the nucleolus is formed. Cytokinesis begins
What is cytokinesis
The actual division of the cells into two separate cells. begins during Telophase