3.6 Structure Of Protiens Flashcards

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1
Q

What molecules are peptides and polymers made up of

A

Amino acids

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2
Q

What do proteins consist of

A

One or more polypeptides arranged as complex macromolecules

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3
Q

What elements do all proteins contain

A

Carbon, oxygen, hydrogen and nitrogen

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4
Q

What causes differences in the amino acids

A

R-groups

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5
Q

How does the synthesis of peptides take place

A

Amino acids join when the amine and carboxylic acid groups connected to the central carbon atoms react

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6
Q

How are peptide bonds formed

A

It is formed during a condensation reaction between amino acids hydroxyl in the carboxylic group of one amino acid and a hydrogen in the Amine group of another

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7
Q

What is the resulting compound of the synthesis of peptides

A

A dipeptide

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8
Q

What is formed when many amino acids are joined together by peptide bonds

A

A polypeptide

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9
Q

What are the levels of protein structure

A

Primary, secondary, tertiary

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10
Q

What is the primary structure

A

He sequence in which the amino acids are joined

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11
Q

How is the primary structure sequence directed

A

Directed by information carried with DNA

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12
Q

In the primary structure what do amino acids influence

A

They influence how the polypeptide folds to give the protein it’s final shape determining its function

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13
Q

What are the only bonds involved in the primary structure of a protein

A

Peptide bonds

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14
Q

What interacts in the secondary structure

A

The oxygen, hydrogen and nitrogen atoms of the basic repeating structure interact

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15
Q

What other bonds may form within the amino acid

Secondary structure

A

Hydrogen bonds

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16
Q

What do the hydrogen bonds cause the structure to do

Secondary structure

A

Pull thee structure into a coil shape (alpha helix)

17
Q

Other than within the amino acid chain, how/where may hydrogen bonds form
(Secondary structure)

A

Between two polypeptide chains which can lie parallel to each other

18
Q

What is it called when polypeptide chains lie parallel to each other
(Secondary structure)

A

Beta pleated sheets

19
Q

Summarise the secondary structure

A

The result of hydrogen bonding at regions along protein molecules depending on the amino acid sequences

20
Q

What is the tertiary structure

A

The folding of a protein into its final shape

21
Q

How does further folding of the protein occur

Tertiary structure

A

The coiling/folding of the structure brings R-groups close enough together to interact causing further folding to occur

22
Q

What are the interactions that occur between the R-groups

A

Hydrophobic and hydrophilic interactions
Hydrogen bonds
Ionic bonds
Disulfade bonds

23
Q

What do ionic bonds form between

A

Form between oppositely charged r groups

24
Q

What are disulfide bonds

A

Covalent bonds and the strongest of the bonds that form only between r groups that contain sulfur atoms

25
Q

Which are the weakest bonds in protein structures

A

Hydrogen bonds

26
Q

Which are the strongest bonds in protein structures

A

Disulfide bonds

27
Q

What is the quaternary structure

A

Results from the association of two or more individual proteins called subunits which interact the same way as the tertiary structure except they are between different protein molecules

28
Q

In what environment are proteins assembled in the cytoplasm

A

Aqueous

29
Q

What determines how the protein folds in the cytoplasm

A

Whether the r groups are hydrophilic or hydrophobic

30
Q

How are peptides created

A

By amino acids linking together in condensation reactions to form peptide bonds

31
Q

What are proteases

A

Enzymes that catalyse the reverse reaction, turning the peptides back into amino acids

32
Q

What is used to break the peptide bond in a hydrolysis reaction

A

A water molecule