6 - Receptors and Membrane Turnover Flashcards
Describe and compare biological communication processes involving hormones, local mediators and neurotransmitters
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Give an overview of the role of membrane proteins as receptors for responding to external stimuli, and for the uptake of external molecules via endocytosis
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Contrast, in general terms, the mechanisms of polypeptide hormones and the steriod and thyroid hormones
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Discuss the principles of communication between cells via chemical messengers in the paracrine, endocrine and nervous systems
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Describe the role of receptors in transducing the information carried by an extracellular hydrophilic signalling molecule across a hydrophobic cellular membrane bilayer
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Explain the concept of receptor super-families, based on common structural motifs
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Describe the mechanisms employed by the four major classes of receptors involved in cellular signalling via hormones, local mediators and neurotransmitters
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Describe the process of receptor-mediated endocytosis
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Give examples of how receptor-mediated endocytosis can contribute to the uptake of metabolites
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Give examples of how receptor-mediated endocytosis can contribute to the passage of large molecules across cells
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Give examples of how receptor-mediated endocytosis can contribute to the control of receptor number at the cell surface
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Give examples of how receptor-mediated endocytosis can contribute to the entry of membrane-enveloped viruses
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