1 - Lipids, Proteins and Membrane Structure

Question 1

List the main kind of lipids and general populations of fatty acids. Describe the properties of amphipathic molecules and explain the proecess of formation of lipid bilayers

Answer 1

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Question 2

Distinguish peripheral from integral membrane proteins and explain the forces associating them with the membrane

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Question 3

Describe in general terms the mechanism of membrane insertion of integral proteins and the features of these proteins which explains their topology in the membrane. Discuss membrane asymmetry.

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Question 4

Discuss the influence of unsaturated fatty acids and cholesterol on membrane fluidity. Describe the main features if the fluid mosaic model of membrane structure and explain the restrictions on protein movement in the membrane, including potential interactions with cytoskeletal elements

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Question 5

Describe the main functions of biological membranes

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Question 6

Describe the composition of biological membranes

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Question 7

Describe the properties of a fluid membrane

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Question 8

Describe the contribution of cholesterol to membrane stability

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Question 9

Outline the evidence for membrane proteins

Answer 9

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Question 10

Describe how membrane proteins associate with the lipid bilayer

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Question 11

Describe how membrane proteins may move

Answer 11

Lateral rotation, NO FLIP-FLOP!! etc.

Question 12

Describe how membrane proteins contribute to the cytoskeleton

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Question 13

Describe how membrane proteins are inserted into membranes

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Question 14

Discuss how the correct orientation of membrane proteins is achieved

Answer 14

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