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Membranes & Receptors > 2 - Membrane Permeability/ Cell Volume and pH regulation > Flashcards

2 - Membrane Permeability/ Cell Volume and pH regulation Flashcards

1
Q

Discuss the properties of solutes which affect their movement through membranes. Distinguish passive diffusion, facilitated and active transport. Describe the general features of channel proteins

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2
Q

Compare the proposed transport mechanisms of the plasma membrane Na/K+-ATPase, the plasma membrane and sarcoplasmic reticulum Ca2+-ATPases, and the Na+/Ca++-exchanger in regulating ion concentrations inside cells

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3
Q

Describe the pumping of sugars, amino acids and ions by mammalian cells, using symports and antiports driven by the Na+ gradient. Understand the regulation of cytoplasm pH via the Na+/H+-exchanger and the Cl-/HCO3–exchanger

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4
Q

Discuss the principles of solute movement across biological membranes

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5
Q

Distinguish passive diffusion, facilitated transport and active transport across membranes

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6
Q

Define the terms uniport, cotransport, symport and antiport

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7
Q

Outline the major physiological roles of sodium-potassium ATPase (Na+-K+-ATPase, Na pump)

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8
Q

Outline the major physiological roles of plasma membrane Ca++ATPase (PMCA)

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9
Q

Outline the major physiological roles of Sarco(endo)plasmic reticulum ATPase (SERCA)

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10
Q

Outline the major physiological roles of sodium calcium exchange (NCX)

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11
Q

Outline the major physiological roles of sodium hydrogen exchange (NHX)

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12
Q

Outline the major physiological roles of anion exchange (AE)

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13
Q

Discuss how ion transporters work together in cell physiology

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14
Q

Discuss how ion transport contributes to control of resting intracellular Ca++ concentration

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15
Q

Discuss how ion transport contributes to cellular pH regulation

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16
Q

Discuss how ion transport contributes to cell volume regulation

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17
Q

Discuss how ion transport contributes to renal bicarbonate reabsorption

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18
Q

Discuss how ion transport contributes to renal Na+ handling

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19
Q

Indicate the approximate volumes of fluid filled compartment in the body

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20
Q

Describe important membrane transport mechanisms involved in the control of intracellular Na+, K+ and Ca++ concentrations

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21
Q

Discuss how ion transport contributes to the regulation of cell volume

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22
Q

Discuss how ion transport contributes to the regulation of intracellular pH

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23
Q

Describe the transport of sugars and amino acids across mammalian cell membranes by passive and active trasporters in different tissues

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Membranes & Receptors (8 decks)

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